2'-Hydroxy-3-phenylpropiophenone
- CAS NO.：3516-95-8
- Empirical Formula: C15H14O2
- Molecular Weight: 226.27
- MDL number: MFCD00002221
- EINECS: 222-521-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 00:38:59
What is 2'-Hydroxy-3-phenylpropiophenone?
Chemical properties
Slightly Yellow Crystals
The Uses of 2'-Hydroxy-3-phenylpropiophenone
A metabolite of Propafenone (P757500).
The Uses of 2'-Hydroxy-3-phenylpropiophenone
2’-Hydroxy-3-phenylpropiophenone (Propafenone EP Impurity A; Propafenone BP Impurity A; Propafenone USP Impurity A) is a metabolite of Propafenone (P757500).
General Description
2′-Hydroxy-3-phenylpropiophenone is a colorless to yellow liquid or solid. 2′-Hydroxy-3-phenylpropiophenone derivatives show antiarrhythmic,spasmolytic and local anaesthetic activities.
Properties of 2'-Hydroxy-3-phenylpropiophenone
| Melting point: | 36-37 °C(lit.) |
| Boiling point: | 158°C/2mmHg(lit.) |
| Density | 1.150±0.06 g/cm3(Predicted) |
| refractive index | n |
| Flash point: | >230 °F |
| storage temp. | Refrigerator |
| solubility | Chloroform (Slightly), Dichloromethane (Slightly), Ethyl Acetate (Slightly), Eth |
| form | Solid |
| pka | 8.07±0.30(Predicted) |
| color | Off-White Low Melting |
| λmax | 324nm(MeOH)(lit.) |
| CAS DataBase Reference | 3516-95-8(CAS DataBase Reference) |
| EPA Substance Registry System | 1-Propanone, 1-(2-hydroxyphenyl)-3-phenyl- (3516-95-8) |
Safety information for 2'-Hydroxy-3-phenylpropiophenone
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2'-Hydroxy-3-phenylpropiophenone
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