4-NITROPHENETOLE
- CAS NO.：100-29-8
- Empirical Formula: C8H9NO3
- Molecular Weight: 167.16
- MDL number: MFCD00007330
- EINECS: 202-837-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 01:13:21
What is 4-NITROPHENETOLE?
Chemical properties
brown crystalline solid
Physical properties
4-Ethoxynitrobenzene, crystallizes from ethanol as prisms, which are insoluble in water and moderately soluble in ethanol or ether.
The Uses of 4-NITROPHENETOLE
Dyes and other intermediates.
The Uses of 4-NITROPHENETOLE
Reduction of 4-Ethoxynitrobenzene gives p-phenetidine [156-43-4], which undergoes similar reactions to p-anisidine and is also the intermediate for the analgesic phenacetin (4-ethoxyacetanilide [62- 44-2]) and the sweetener dulcin (4-ethoxyphenylurea [150-69-6]).
Synthesis Reference(s)
Canadian Journal of Chemistry, 57, p. 1887, 1979 DOI: 10.1139/v79-299
Journal of the American Chemical Society, 88, p. 1839, 1966 DOI: 10.1021/ja00960a062
Properties of 4-NITROPHENETOLE
| Melting point: | 56-60 °C |
| Boiling point: | 112-115 °C (3 mmHg) |
| Density | 1.1176 |
| refractive index | 1.5475 (estimate) |
| form | powder to crystal |
| color | White to Orange to Green |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 100-29-8(CAS DataBase Reference) |
| NIST Chemistry Reference | 1-Ethoxy-4-nitrobenzene(100-29-8) |
| EPA Substance Registry System | p-Nitrophenetole (100-29-8) |
Safety information for 4-NITROPHENETOLE
Computed Descriptors for 4-NITROPHENETOLE
New Products
Cis-Tosylate 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-One Dibenzo[b,f][1,4]thiazepin-11(10H)-one Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) N-BOC-piperidine-4-carboxylic acid 1-Benzhydrylazetane-3-carbonitrile AMINO-(3-CHLORO-PHENYL)-ACETIC ACID 2-(2-Chlorophenyl)glycine (±)-amino(2-fluorophenyl)acetic acid 8-oxa-1,3-diazaspiro[4.5]decane-2,4-dione BENZOIC ACID-D METHANE SULFONIC ACID-D4 PHOSPORIC ACID-D3 85 W% IN D2O DEUTERIUM OXIDE FOR NMR TOLUENE-D3 BENZENE-D6 1-Acetyl-4-(4-hydroxyphenyl)piperazine 1-(3-Chlorophenyl)piperazine hydrochlorideRelated products of tetrahydrofuran
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