4-Hydroxy-3-nitropyridine
- CAS NO.：5435-54-1
- Empirical Formula: C5H4N2O3
- Molecular Weight: 140.1
- MDL number: MFCD00128874
- EINECS: 611-127-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-09-11 17:37:59
What is 4-Hydroxy-3-nitropyridine?
Chemical properties
Light yellow crystalline powder
The Uses of 4-Hydroxy-3-nitropyridine
4-Hydroxy-3-nitropyridine may be used in the synthesis of 4-ethoxy-3-nitropyridine by treating with phosphorus pentachloride (PCl5) followed by ethanol. It may also be used to prepare 4-chloro-3-nitropyridine by treating with PCl5-POCl3 (phosphorus oxychloride).
General Description
4-Hydroxy-3-nitropyridine can be synthesized by the nitration of 4-hydroxypyridine.
Properties of 4-Hydroxy-3-nitropyridine
| Melting point: | 285 °C (dec.) (lit.) |
| Boiling point: | 382.1±22.0 °C(Predicted) |
| Density | 1.507±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| pka | 0.13±0.14(Predicted) |
| BRN | 1072928 |
| CAS DataBase Reference | 5435-54-1(CAS DataBase Reference) |
Safety information for 4-Hydroxy-3-nitropyridine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 4-Hydroxy-3-nitropyridine
| InChIKey | YUWOLBZMQDGRFV-UHFFFAOYSA-N |
4-Hydroxy-3-nitropyridine manufacturer
GK Chemicals
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product: 4-Hydroxy-3-nitropyridine 98%
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