3-Nitro-2-pyridinol
Synonym(s):3-Nitro-2-pyridinol;3-Nitro-2-pyridone
- CAS NO.：6332-56-5
- Empirical Formula: C5H4N2O3
- Molecular Weight: 140.1
- MDL number: MFCD00006270
- EINECS: 228-709-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-09-11 14:58:18
What is 3-Nitro-2-pyridinol?
Chemical properties
yellow to yellow-brown cryst. powder or needles
The Uses of 3-Nitro-2-pyridinol
2-Hydroxy-3-nitropyridine was used in the synthesis of:
- 3-nitro-2-pyridyl β-D-galactoside
- 3-nitro-2-pyridyl N-acetyl-β-D-glucosaminide
- 5-amino-6-chloro-3-iodopyridine
Synthesis Reference(s)
Tetrahedron Letters, 12, p. 2211, 1971 DOI: 10.1016/S0040-4039(01)96822-4
General Description
2-Hydroxy-3-nitropyridine reacts with phosphorus pentachloride and phosphoryl chloride to yield 2-chloro-3-nitropyridine.
Properties of 3-Nitro-2-pyridinol
| Melting point: | 212 °C (dec.) (lit.) |
| Boiling point: | 256.56°C (rough estimate) |
| Density | 1.5657 (rough estimate) |
| refractive index | 1.4800 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| form | powder to crystal |
| pka | 8.37±0.10(Predicted) |
| color | yellow |
| BRN | 124474 |
| CAS DataBase Reference | 6332-56-5(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Hydroxy-3-nitropyridine(6332-56-5) |
Safety information for 3-Nitro-2-pyridinol
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3-Nitro-2-pyridinol
| InChIKey | BOAFCICMVMFLIT-UHFFFAOYSA-N |
3-Nitro-2-pyridinol manufacturer
GK Chemicals
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product: 6332-56-5 2-Hydroxy-3-nitropyridine 98%
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