3-Nitropyridine
- CAS NO.:2530-26-9
- Empirical Formula: C5H4N2O2
- Molecular Weight: 124.1
- MDL number: MFCD00234974
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02
What is 3-Nitropyridine?
Chemical properties
white to yellow needle-like crystals
The Uses of 3-Nitropyridine
3-Nitropyridine is used in the novel synthesis of biologically active nitro heterocyclic compounds.
Synthesis
In 1993 Suzuki and co-workers reported the nitration of pyridine with nitrogen dioxide and ozone in dichloromethane at room temperature. They obtained a 3.5 % yield of 3-nitropyridine and 1.2 % of 3,5-dinitropyridine. 
3-Nitropyridines can also be synthesized by oxidation of 3-aminopyridine with hydrogen peroxide in fuming sulphuric acid in 45% yield. Nitration of 2,6-dichloropyridine with nitronium tetrafluoroborate gave a 11% yield of 3-nitropyridine after dehalogenation. 3-nitropyridine has also been prepared from 2- chloro-3-nitropyridine.
Properties of 3-Nitropyridine
| Melting point: | 35-40 °C |
| Boiling point: | 216°C |
| Density | 1,33 g/cm3 |
| refractive index | 1.4800 (estimate) |
| Flash point: | 216°C |
| storage temp. | Flammables area |
| solubility | soluble in Methanol |
| pka | pK1:0.79(+1) (25°C,μ=0.02) |
| form | Liquid |
| color | Clear colorless |
| BRN | 111969 |
| CAS DataBase Reference | 2530-26-9(CAS DataBase Reference) |
Safety information for 3-Nitropyridine
| Signal word | Danger |
| Pictogram(s) |
![]() Corrosion Corrosives GHS05 ![]() Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. |
Computed Descriptors for 3-Nitropyridine
3-Nitropyridine manufacturer
GK Chemicals
1Y
Phone:+91-7207279444
Whatsapp: +91-7207279444
product: 2530-26-9 3-Nitropyridine 98%
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