4-AZIDOPHENACYL BROMIDE
Synonym(s):4′-Azido-2-bromoacetophenone;4-Azido-α-bromoacetophenone
- CAS NO.：57018-46-9
- Empirical Formula: C8H6BrN3O
- Molecular Weight: 240.06
- MDL number: MFCD00042637
- EINECS: 260-519-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 00:56:34
What is 4-AZIDOPHENACYL BROMIDE?
Chemical properties
4-AZIDOPHENACYL BROMIDE is off-White Crystalline Solid
The Uses of 4-AZIDOPHENACYL BROMIDE
4-AZIDOPHENACYL BROMIDE is a versatile photolabile bifunctional reagent. Useful for investigating the active sites of sulfhydryl enzymes-particularly those which posess a particularly reactive cysteine residue at the active site. Used to study the nature of the ribosomal binding site of E. coli tRNAVal.
The Uses of 4-AZIDOPHENACYL BROMIDE
Photoactive, heterobifunctional cross-linking reagent. Typically, the initial reaction couples to sulfhydryl in the pH range 7.0-8.0. Second bonding occurs during UV irradiation (250 nm) via reactive nitrene. The latter bonding is rapid and non-specific.
What are the applications of Application
p-Azidophenacyl Bromide is an aryl azide-based, sulfhydryl- and photoreactive crosslinker
Properties of 4-AZIDOPHENACYL BROMIDE
| Melting point: | 64-65 °C |
| storage temp. | 2-8°C |
| solubility | methanol: 50 mg/mL |
| form | powder |
| color | yellow |
| BRN | 1961705 |
| Stability: | Light, Temperature And Moisture Sensitive, Temperature and Moisture sensitive |
Safety information for 4-AZIDOPHENACYL BROMIDE
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Corrosion Corrosives GHS05  Health Hazard GHS08 |
| GHS Hazard Statements |
H228:Flammable solids H314:Skin corrosion/irritation H317:Sensitisation, Skin H334:Sensitisation, respiratory |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P310:Immediately call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-AZIDOPHENACYL BROMIDE
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