(3S)-3-[[3-[[4-(Trifluoromethyl)benzoyl]amino]phenyl]methoxy]-L-aspartic acid
- CAS NO.：480439-73-4
- Empirical Formula: C19H17F3N2O6
- Molecular Weight: 426.34
- MDL number: MFCD09971089
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:52:40
![(3S)-3-[[3-[[4-(Trifluoromethyl)benzoyl]amino]phenyl]methoxy]-L-aspartic acid Structural](https://img.chemicalbook.in/CAS/GIF/480439-73-4.gif)
What is (3S)-3-[[3-[[4-(Trifluoromethyl)benzoyl]amino]phenyl]methoxy]-L-aspartic acid?
The Uses of (3S)-3-[[3-[[4-(Trifluoromethyl)benzoyl]amino]phenyl]methoxy]-L-aspartic acid
TFB-TBOA is a novel glutamate transporter blocker.
Biological Activity
High affinity, selective blocker of glial glutamate transporters EAAT1 and EAAT2 (IC 50 values are 17, 22 and 300 nM for EAAT2, EAAT1 and EAAT3 respectively). Displays no activity on a wide range of neurotransmitter receptors and transporters. Induces convulsions following i.c.v. administration in mice.
Storage
Store at -20°C
Properties of (3S)-3-[[3-[[4-(Trifluoromethyl)benzoyl]amino]phenyl]methoxy]-L-aspartic acid
| Boiling point: | 513.6±50.0 °C(Predicted) |
| Density | 1.500±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Soluble to 100 mM in DMSO |
| form | Powder |
| pka | 2.05±0.27(Predicted) |
| color | White to off-white |
Safety information for (3S)-3-[[3-[[4-(Trifluoromethyl)benzoyl]amino]phenyl]methoxy]-L-aspartic acid
Computed Descriptors for (3S)-3-[[3-[[4-(Trifluoromethyl)benzoyl]amino]phenyl]methoxy]-L-aspartic acid
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