DL-threo-beta-Hydroxyaspartic acid
Synonym(s):threo-2-Amino-3-hydroxysuccinic acid
- CAS NO.：4294-45-5
- Empirical Formula: C4H7NO5
- Molecular Weight: 149.1
- MDL number: MFCD00036749
- EINECS: 224-299-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:49:20
What is DL-threo-beta-Hydroxyaspartic acid?
Chemical properties
Off-White Solid
The Uses of DL-threo-beta-Hydroxyaspartic acid
A glutamate uptake inhibitor
The Uses of DL-threo-beta-Hydroxyaspartic acid
L-aspartate beta-carboxylase inhibitor, neurotoxic
The Uses of DL-threo-beta-Hydroxyaspartic acid
DL-threo-β-Hydroxyaspartic acid (THA) has been used to block glutamate transport in cannulated sprague dawley rat.
What are the applications of Application
D,L-threo-β-Hydroxyaspartic acid is a glutamate uptake inhibitor
Definition
ChEBI: (3S)-3-hydroxy-L-aspartic acid is the (3S)-diastereomer of 3-hydroxy-L-aspartic acid. It has a role as a metabolite. It is a conjugate acid of a (3S)-3-hydroxy-L-aspartate(2-) and a (3S)-3-hydroxy-L-aspartate(1-). It is an enantiomer of a (3R)-3-hydroxy-D-aspartic acid.
General Description
DL-threo-β-hydroxyaspartic acid (THA) is a glutamate uptake inhibitor.
Properties of DL-threo-beta-Hydroxyaspartic acid
| Melting point: | >230°C dec |
| Boiling point: | 368.7±42.0 °C(Predicted) |
| Density | 1.738±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Aqueous Base (Slightly) |
| form | Solid |
| pka | 2.13±0.27(Predicted) |
| color | White to Pale Beige |
| Stability: | Hygroscopic |
| CAS DataBase Reference | 4294-45-5 |
Safety information for DL-threo-beta-Hydroxyaspartic acid
Computed Descriptors for DL-threo-beta-Hydroxyaspartic acid
| InChIKey | YYLQUHNPNCGKJQ-JCYAYHJZSA-N |
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![(3S)-3-[[3-[[4-(TRIFLUOROMETHYL)BENZOYL]AMINO]PHENYL]METHOXY]-L-ASPARTIC ACID](https://img.chemicalbook.in/CAS/GIF/480439-73-4.gif)
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