3,7-Dimethyl-1-propargylxanthine
Synonym(s):3,7-Dimethyl-1-(2-propynyl)xanthine;DMPX
- CAS NO.：14114-46-6
- Empirical Formula: C10H10N4O2
- Molecular Weight: 218.21
- MDL number: MFCD00078576
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:48:27
What is 3,7-Dimethyl-1-propargylxanthine?
Chemical properties
White Solid
The Uses of 3,7-Dimethyl-1-propargylxanthine
3,7-Dimethyl-1-propargylxanthine (DMPX) has been used as an A2 -adenosine receptor (AR) antagonist:
- to study its effects on potential modulation of motor output elicited by epidural spinal stimulation (ESS)
- to study the role of A2a?receptor in elevating cyclic adenosine monophosphate (cAMP) levels
- to study its effects on the cell viability of human gastric cancer cell line
The Uses of 3,7-Dimethyl-1-propargylxanthine
A selective A2 adenosine receptor antagonist. Pharmacology: Ki vs [3H]NECA at A2 receptors in rat striatal membranes: 11± 3 uM; Ki vs [3H]CHA at A1 receptors in rat cerebral cortical membranes: 45 ± 4 uM.
What are the applications of Application
3,7-Dimethyl-1-propargylxanthine is a selective A2 adenosine receptor antagonist
Biochem/physiol Actions
3,7-Dimethyl-1-propargylxanthine (DMPX) is a caffeine analog and A2-selective adenosine receptor (AR) antagonist.
Properties of 3,7-Dimethyl-1-propargylxanthine
| Melting point: | 204-205°C |
| storage temp. | -20°C Freezer |
| solubility | DMSO: ≥15 mg/mL |
| form | solid |
| color | white |
| CAS DataBase Reference | 14114-46-6 |
Safety information for 3,7-Dimethyl-1-propargylxanthine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3,7-Dimethyl-1-propargylxanthine
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![3-HYDROXYPROPYL-7-METHYL-8-(3-METHOXYSTYRYL)-1-PROPARGYLXANTHINE, [METHYL-3H]](https://img.chemicalbook.in/StructureFile/ChemBookStructure4/GIF/CB2753407.gif)
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