DMT-dC(ac) Phosphoramidite
Synonym(s):DMT-dC(ac) Amidite;N4-Acetyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxycytidine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite];N-acetyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxycytidine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
- CAS NO.：154110-40-4
- Empirical Formula: C41H50N5O8P
- Molecular Weight: 771.84
- MDL number: MFCD09842112
- EINECS: 2017-001-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:19:11
What is DMT-dC(ac) Phosphoramidite ?
Chemical properties
White or off-white power
The Uses of DMT-dC(ac) Phosphoramidite
Ac-dC phosphoramidite is a nucleoside used in the preparation of cytidine-?based nucleotide-?lipids which can act as supramolecular gelators depending on both the nucleobase and the presence of salts.
Definition
5'-O-DMT-N4-Acetyl-2'-Deoxycytidine-CE phosphoramidite (DMT-dC(ac) Phosphoramidite) is a cytidine phosphoramidite monomer that can be applied to make oligodeoxynucleotides.
Storage
-20°C, protect from light, stored under nitrogen. In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen).
Properties of DMT-dC(ac) Phosphoramidite
| storage temp. | -20°C |
| solubility | DMSO : 100 mg/mL (129.56 mM; Need ultrasonic) |
| form | powder |
| pka | 10.26±0.20(Predicted) |
| color | white to off-white |
Safety information for DMT-dC(ac) Phosphoramidite
Computed Descriptors for DMT-dC(ac) Phosphoramidite
| InChIKey | MECWEBCHRKVTNV-QQIWIMIASA-N |
| SMILES | O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C=CC(NC(C)=O)=NC2=O)C[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N |&1:25,27,40,r| |
DMT-dC(ac) Phosphoramidite manufacturer
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product: 154110-40-4 98%
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![N-Benzoyl-5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]adenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite](https://img.chemicalbook.in/CAS/GIF/104992-55-4.gif)
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