2,3,5,6-TETRAFLUORO-4-PYRIDINE-CARBONITRILE
- CAS NO.：16297-07-7
- Empirical Formula: C6F4N2
- Molecular Weight: 176.07
- MDL number: MFCD00075302
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 01:54:46
What is 2,3,5,6-TETRAFLUORO-4-PYRIDINE-CARBONITRILE?
The Uses of 2,3,5,6-TETRAFLUORO-4-PYRIDINE-CARBONITRILE
2,3,5,6-Tetrafluoro-4-pyridinecarbonitrile may be used in the preparation of 2-anilino-3,5,6-trifluoroisonicotinonitrile.
General Description
2,3,5,6-Tetrafluoro-4-pyridinecarbonitrile is a perfluorinated heteroaromatic compound. 2,3,5,6-Tetrafluoro-4-pyridinecarbonitrile (tetrafluoro-4-cyanopyridine) reacts with 1,3-dicarbonyl systems to yield the corresponding [5,6]-ring fused furo derivatives. 2,3,5,6-Tetrafluoro-4-pyridinecarbonitrile (4-cyanotetrafluoropyridine) reacts with amidines to yield [6,6]-fused pyrimidinopyridine system via nucleophilic substitution at the C-3 position of the pyridine ring followed by intramolecular cyclization onto the pendant cyano group. Reaction of 2,3,5,6-tetrafluoro-4-pyridinecarbonitrile (4-cyanotetrafluoropyridine) with sulfur centred nucleophiles has been reported.
Properties of 2,3,5,6-TETRAFLUORO-4-PYRIDINE-CARBONITRILE
| Melting point: | 66-68 °C (lit.) |
| Boiling point: | 166.1±35.0 °C(Predicted) |
| Density | 1.56±0.1 g/cm3(Predicted) |
| pka | -14.32±0.28(Predicted) |
| form | crystalline powder |
| color | White |
Safety information for 2,3,5,6-TETRAFLUORO-4-PYRIDINE-CARBONITRILE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2,3,5,6-TETRAFLUORO-4-PYRIDINE-CARBONITRILE
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