2,3,5-Trichloropyridine
- CAS NO.：16063-70-0
- Empirical Formula: C5H2Cl3N
- Molecular Weight: 182.44
- MDL number: MFCD00043007
- EINECS: 407-270-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-09-25 17:15:13
What is 2,3,5-Trichloropyridine?
Chemical properties
Beige powder
The Uses of 2,3,5-Trichloropyridine
2,3,5-Trichloropyridine may be used in the synthesis of 3,5-dichloro-2-arylpyridines via palladium acetate-catalyzed ligand-free Suzuki reaction with arylboronic acids.
General Description
Separation and migration behavior of 2,3,5-trichloropyridine has been studied by micellar electrokinetic chromatography. Crystal structure of 2,3,5-trichloropyridine has been reported. Mol-ecules of 2,3,5-trichloropyridine in crystal are stacked along the short a axis and forms a layer structure. 2,3,5-Trichloropyridine is reported to undergo nucleophilic displacement reaction in ionic liquid to afford the corresponding 2-aryloxylpropionate.
Properties of 2,3,5-Trichloropyridine
| Melting point: | 46-50 °C (lit.) |
| Boiling point: | 219 °C (lit.) |
| Density | 1.539±0.06 g/cm3(Predicted) |
| Flash point: | >230 °F |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | Solid |
| pka | -2.92±0.10(Predicted) |
| color | Off-white to pale yellow |
| Water Solubility | Slightly soluble in water. |
| BRN | 119384 |
| InChI | InChI=1S/C5H2Cl3N/c6-3-1-4(7)5(8)9-2-3/h1-2H |
| CAS DataBase Reference | 16063-70-0(CAS DataBase Reference) |
Safety information for 2,3,5-Trichloropyridine
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H317:Sensitisation, Skin H318:Serious eye damage/eye irritation H412:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2,3,5-Trichloropyridine
| InChIKey | CNLIIAKAAMFCJG-UHFFFAOYSA-N |
| SMILES | C1(Cl)=NC=C(Cl)C=C1Cl |
2,3,5-Trichloropyridine manufacturer
SAKEM LLP
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product: 2,3,5-Trichloropyridine 16063-70-0 98%
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