2,3-DIHYDRO-1,4-BENZODIOXIN-2-YLMETHYLAMINE
Synonym(s):(2,3-Dihydrobenzo-1,4-dioxin-2-yl)methylamine;1,4-Benzodioxane-2-methylamine;2,3-Dihydro-1,4-benzodioxin-2-methanamine
- CAS NO.：4442-59-5
- Empirical Formula: C9H11NO2
- Molecular Weight: 165.19
- MDL number: MFCD00203985
- EINECS: 224-671-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 01:01:34
What is 2,3-DIHYDRO-1,4-BENZODIOXIN-2-YLMETHYLAMINE?
The Uses of 2,3-DIHYDRO-1,4-BENZODIOXIN-2-YLMETHYLAMINE
2-Aminomethyl-1,4-benzodioxane is used in the synthesis of N-substituted (dihydrobenzodioxinyl)methylamine derivatives as D2 antagonists/5-HT1A partial agonists with potential as atypical antipsychotic agents in relation to affinity for α1 adrenoceptors.
Properties of 2,3-DIHYDRO-1,4-BENZODIOXIN-2-YLMETHYLAMINE
| Melting point: | 184-188 °C |
| Boiling point: | 105-110 °C/3 mmHg |
| Density | 1.1679 g/mL at 25 °C |
| refractive index | n20/D 1.5594 |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | Chloroform, Ethyl Acetate |
| form | Oil |
| pka | 8.88±0.29(Predicted) |
| color | Clear Colorless |
| CAS DataBase Reference | 4442-59-5(CAS DataBase Reference) |
Safety information for 2,3-DIHYDRO-1,4-BENZODIOXIN-2-YLMETHYLAMINE
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. |
Computed Descriptors for 2,3-DIHYDRO-1,4-BENZODIOXIN-2-YLMETHYLAMINE
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