SPIROXATRINE
- CAS NO.：1054-88-2
- Empirical Formula: C22H25N3O3
- Molecular Weight: 379.45
- MDL number: MFCD00055134
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-27 17:00:41
What is SPIROXATRINE?
The Uses of SPIROXATRINE
Spiroxatrine (R 5188) is a SR-1A antagonist.
What are the applications of Application
Spiroxatrine (R 5188) is a SR-1A antagonist
Definition
ChEBI: 8-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one is a member of imidazolidines.
Biological Activity
5-HT 1A antagonist. More active and selective than spiperone. Also a very potent α 2C adrenergic receptor antagonist.
Properties of SPIROXATRINE
| Melting point: | 215.8-218.0 °C |
| Boiling point: | 602.8±55.0 °C(Predicted) |
| Density | 1.32±0.1 g/cm3(Predicted) |
| storage temp. | Store at RT |
| solubility | 0.1 M HCl: moderately soluble |
| form | powder |
| pka | 15.03±0.20(Predicted) |
| color | white |
Safety information for SPIROXATRINE
Computed Descriptors for SPIROXATRINE
New Products
2-Bromo-4-hydroxypyridine Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) Dibenzo[b,f][1,4]thiazepin-11(10H)-one 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-One Cis-Tosylate 1-(4-methoxyphenyl)-4-(4-Nitrophenyl)Piperazine (IT-1) 1-aminocyclobutanecarbonitrile hydrochloride AMINO-O-TOLYL-ACETIC ACID 1-Aminocyclobutanecarboxylic Acid Hydrochloride AMINO(2-BROMOPHENYL)ACETIC ACID 6-BROMOTETRAZOLO[1,5-A]PYRIDINE 3-Oxocyclobutanecarboxylic acid METHANOL-D1(OD) TERTIARY BUTANOL-D9 N-ETHYL-D5-AMINE HYDROCHLORIDE BENZOIC ACID-D CHLOROFORM-D TOLUENE-D3 2-(2-Bromophenyl)ethanol Boc-D-Glu(OMe)-OMe 2,5 Dibromopyridine Ethyl 4-hydroxy-3-oxobutanoate Dimethyl (2S)-2-((tert-butoxycarbonyl)amino)-4-(cyanomethyl)pentanedioate 1-(3-Chlorophenyl)piperazine hydrochlorideRelated products of tetrahydrofuran
![1-[2-(2-METHOXYPHENOXY)ETHYL]-PIPERIDINE](https://img.chemicalbook.in/CAS/GIF/105602-16-2.gif)
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