2-Methylpiperidine
Synonym(s):α-Pipecoline;2-Pipecoline;NSC 31047;NSC 462
- CAS NO.：109-05-7
- Empirical Formula: C6H13N
- Molecular Weight: 99.17
- MDL number: MFCD00005982
- EINECS: 203-642-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-03 14:17:14
What is 2-Methylpiperidine?
Chemical properties
CLEAR YELLOW LIQUID
Chemical properties
Colorless to yellow liquid; pepper-like aroma.
The Uses of 2-Methylpiperidine
2-Methylpiperidine, is used for the oxidation of secondary amines to nitrones by means of H2O2 catalyzed by Sodium tungsten oxide dihydrate.
The Uses of 2-Methylpiperidine
Reactant for C-2 arylation of piperidines through directed transition metal-catalyzed sp3 C-H activation1Reactant for synthesis of:• ;Azepan-4-ones via two step [5+2] annulation2• ;2-Aminobenzoxazoles3• ;Unsymmetrically substituted ureas4• ;Corticotropin-releasing factor receptor type 1 antagonists5• ;Gefitinib analogues with anti-tumor activity6
Definition
ChEBI: 2-Methylpiperidine is a member of piperidines.
Aroma threshold values
High strength; ammoniacal type; recommend smelling in a 1.0% solution or less.
Taste threshold values
Amine, creamy, taco, lettuce taste at 5 ppm in water.
Synthesis Reference(s)
Journal of the American Chemical Society, 111, p. 4108, 1989 DOI: 10.1021/ja00193a056
Properties of 2-Methylpiperidine
| Melting point: | -4--5 °C |
| Boiling point: | 118-119 °C/753 mmHg (lit.) |
| Density | 0.844 g/mL at 25 °C (lit.) |
| refractive index | n |
| FEMA | 4244 | 2-METHYLPIPERIDINE |
| Flash point: | 47 °F |
| storage temp. | Flammables area |
| form | Liquid |
| pka | pK1:10.95(+1) (25°C) |
| color | Clear yellow |
| Odor | at 1.00 % in propylene glycol. amine fishy seafood taco corn chip |
| PH | 12-13 (111g/l, H2O) |
| Water Solubility | soluble |
| JECFA Number | 1608 |
| BRN | 79804 |
| CAS DataBase Reference | 109-05-7(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Methylpiperidine(109-05-7) |
| EPA Substance Registry System | Piperidine, 2-methyl- (109-05-7) |
Safety information for 2-Methylpiperidine
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Corrosion Corrosives GHS05  Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H225:Flammable liquids H302:Acute toxicity,oral H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Methylpiperidine
New Products
Hendecanoic acid 2-Amino-5-cyanopyridine 2-Bromo-5-cyanopyridine DL-3-Amino-3-(2-methoxyphenyl)propionic acid 3-Hydroxypropionitrile 2-AMINO-3-METHYLQUINOLINE HYDROCHLORIDE 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 5-Amino-3-(trifluoromethyl)picolinonitrile 4,6-Dichloro-3-methylpyridazine 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline Trenbolone acetate 3-Methylamino-1,2-propanediol 4-Bromobenzaldehyde 2-Amino-4-phenyl-thiazole 4-Chloro-2-methyl quinoline 2-(Chloromethyl) quinazolin-4(3H)-one 5-Phenyl-[1,3,4]-thiadiazol-2-amine 2-Chloro-6-nitro benzothiazole 1-(3-Hydroxyphenyl)-2-thiourea 3-methyl-8-(trifluoromethyl)quinolin-4-ol N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methacrylamide 1-(4-Aminopiperidin-1-yl)-3,3,3-trifluoropropan-1-one 5-chloro-2-(4-methoxybenzyl)-4-(trifluoromethyl)pyridazin-3(2H)-one 3-cyanocyclohexane-1-carboxylic acidRelated products of tetrahydrofuran
You may like
-
2-Methylpiperidine CAS 109-05-7View Details
109-05-7 -
2-Methylpiperidine, 99% CAS 109-05-7View Details
109-05-7 -
2-Methylpiperidine, 98% CAS 109-05-7View Details
109-05-7 -
2-Methylpiperidine CAS 109-05-7View Details
109-05-7 -
2-Methylpiperidine CAS 109-05-7View Details
109-05-7 -
103095-63-2 DL-3-Amino-3-(2-methoxyphenyl)propionic acid 98+View Details
103095-63-2 -
117391-48-7 98+View Details
117391-48-7 -
3-Hydroxypropionitrile 98+View Details
109-78-4
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.