2-Methoxypyridine
- CAS NO.：1628-89-3
- Empirical Formula: C6H7NO
- Molecular Weight: 109.13
- MDL number: MFCD00006262
- EINECS: 216-623-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:20:23
What is 2-Methoxypyridine?
Chemical properties
Clear colorless to slightly yellow liquid
The Uses of 2-Methoxypyridine
2-Methoxypyridine can be used as an intermediate to synthesize 2-methoxy-3-pyridinesulfonyl chloride which is patented as a reactant used to prepare erythromycin macrolide antibiotics as antibacterial and antiprotozoal agents. It can also be used to prepare bicyclic iminopyrimidinones as Beta Amyloid Cleaving Enzyme-1 (BACE1) inhibitors.
Properties of 2-Methoxypyridine
| Boiling point: | 142 °C (lit.) |
| Density | 1.038 g/mL at 25 °C (lit.) |
| refractive index | n |
| FEMA | 4639 | 2-METHOXYPYRIDINE |
| Flash point: | 90 °F |
| storage temp. | Inert atmosphere,Room Temperature |
| form | Liquid |
| pka | 3.28(at 20℃) |
| color | Clear colorless to slightly yellow |
| Odor | at 0.10?%?in?propylene glycol. green fermented tea |
| Water Solubility | INSOLUBLE |
| JECFA Number | 2156 |
| BRN | 108189 |
| CAS DataBase Reference | 1628-89-3(CAS DataBase Reference) |
| NIST Chemistry Reference | Pyridine, 2-methoxy-(1628-89-3) |
Safety information for 2-Methoxypyridine
| Signal word | Warning |
| Pictogram(s) |
 Flame Flammables GHS02  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H226:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Methoxypyridine
| InChIKey | IWTFOFMTUOBLHG-UHFFFAOYSA-N |
2-Methoxypyridine manufacturer
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