Dibucaine hydrochloride

Chemical properties

white powder

The Uses of Dibucaine hydrochloride

Cinchocaine is used as an anaesthetic agent for spinal anaesthesia; a component in rectal medications used in inflammation of the anus and for the symptomatic treatment of hemorrhoids and fissures in the anus; local anesthetic agent.

The Uses of Dibucaine hydrochloride

Dibucaine HCl is an amide-like quinoline derivative and is one of the most potent and longest acting of the commonly used local anesthetics.

Definition

ChEBI: The monohydrochloride salt of cinchocaine. It is used in creams, ointments and suppositories for temporary relief of pain and itching associated with skin and anorectal conditions.

brand name

Nupercaine (Novartis).

Contact allergens

Dibucaine hydrochloride is an amide group local anesthetic that can induce allergic contact dermatitis.

Safety Profile

Poison by ingestion,subcutaneous, intravenous, intraspinal, parenteral, andintraperitoneal routes. Mutation data reported. A severeeye irritant. A local anesthetic. When heated todecomposition it emits very toxic fumes of HCl and NOx

Mechanism of action

Dibucaine hydrochloride is an amide-type local anesthetic. Local anesthetics block both the initiation and conduction of nerve impulses by decreasing the neuronal membrane's permeability to sodium ions through sodium channel inhibition.