2-Methoxypyrazine
- CAS NO.：3149-28-8
- Empirical Formula: C5H6N2O
- Molecular Weight: 110.11
- MDL number: MFCD00006126
- EINECS: 221-579-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-22 18:57:36
What is 2-Methoxypyrazine?
Description
Methoxypyrazine has an odor threshold of 700 ppb in water. Methoxypyrazine may be prepared from 2-hydroxypyrazine by various routes.
Chemical properties
Colorless liquid
Chemical properties
Methoxypyrazine has a sweet, nutty, cocoa odor. Methoxypyrazine contributes a distinctive “green, capsicum (bell pepper), herbaceous and earthy” aroma that is quite characteristic of certain wines, such as sauvignon blanc and cabernet sauvignon.
Occurrence
Present at ultra-trace levels in sauvignon blanc and cabernet sauvignon grapes and wine. Methoxypyrazine contributes a distinctive wine aroma, even at low parts per trillion levels. Also reported found in cooked beef, cocoa, malt and krill.
Preparation
From 2-hydroxypyrazine by various routes.
Definition
ChEBI: Methoxypyrazine is an aromatic ether and a member of pyrazines.
Aroma threshold values
700 ppb in water
Safety Profile
Skin and eye irritant. When heated to decomposition it emits toxic fumes of NOx.
Properties of 2-Methoxypyrazine
| Boiling point: | 60-61 °C/29 mmHg (lit.) |
| Density | 1.14 g/mL at 25 °C (lit.) |
| refractive index | n |
| FEMA | 3302 | METHOXYPYRAZINE |
| Flash point: | 114 °F |
| storage temp. | Sealed in dry,Room Temperature |
| form | clear liquid |
| pka | 0.53±0.10(Predicted) |
| Specific Gravity | 1.140 |
| color | Colorless to Almost colorless |
| Odor | at 1.00 % in dipropylene glycol. sweet nutty cocoa |
| JECFA Number | 787 |
| BRN | 2241 |
| CAS DataBase Reference | 3149-28-8(CAS DataBase Reference) |
| NIST Chemistry Reference | Pyrazine, methoxy-(3149-28-8) |
| EPA Substance Registry System | Pyrazine, methoxy- (3149-28-8) |
Safety information for 2-Methoxypyrazine
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H226:Flammable liquids H302:Acute toxicity,oral H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Methoxypyrazine
New Products
2-(2-Ethoxyphenoxy)ethyl bromide 1,3-Dibromo-2,2-dimethoxypropane 8-Bromo-7-(2-butynyl)-3-methyl xanthine 5-Chlorothiophene-2-carboxylic acid 8-Bromo-3-methyl xanthine Maleic hydrazide o-Anisaldehyde 4-Bromobenzaldehyde 3-Fluorobenzaldehyde 2-Chlorobenzaldehyde 3-Amino-3-(3-fluorophenyl)propanoic acid 1-Propyl-4-piperidone 2,3-Dihydro-5,6-dimethoxy-2-(4-piperidinylmethyl)-1H-inden-1-one hydrochloride 3-(4-Bromo-3-methyl-2-oxo-2,3-dihydro-1h-benzo[d]imidazol-1-yl)piperidine-2,6-dione 2-Fluoro-6-iodobenzoic acid 3-Pyridineacrylic acid 1-Boc-4-cyanopiperidine ethyl 2-oxo-2,3,9,10-tetrahydro-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxaline-8(7H)-carboxylate Vardenafil Bis-sulphonamide(Dimer) Nitroso Irbesartan N-Nitroso Nortriptyline Sulfonic acid Impurity 2-(p-Tolyl)acetaldehyde 2,2-dibromo-1-cyclopropyl-2-(2-fluorophenyl)ethan-1-oneRelated products of tetrahydrofuran
You may like
-
3149-28-8 2-Methoxypyrazine 98%View Details
3149-28-8 -
2-Methoxypyrazine CAS 3149-28-8View Details
3149-28-8 -
Deuterated Styrene-d8 19361-62-7 97-99%View Details
19361-62-7 -
1187989-89-4 97-99%View Details
1187989-89-4 -
(S)-2-Bromobutanoic acid 97-99%View Details
32659-49-7 -
665020-24-6 ethyl 1-(2,4-dichlorophenyl)-4,5-dihydro-1H-benzo[g]indazole-3-carboxylate 97-99%View Details
665020-24-6 -
3-bromo-[1,1'-biphenyl]-2-amine 1620885-59-7 97-99%View Details
1620885-59-7 -
1503408-77-2 6-Chloro-3,4-dimethylpyridin-2-amine 97-99%View Details
1503408-77-2
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.