2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
- CAS NO.：124489-20-9
- Empirical Formula: C13H12N4O
- Molecular Weight: 240.26
- MDL number: MFCD00870431
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-07-12 17:04:18
What is 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine?
The Uses of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
2-Hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine is a mutagenic metablite of PhIP. PhIP is the most abundant mutagenic heterocyclic amine in cooked foods. Studies have shown the activation of 2-Hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in the formation of PhIP adducts and 5-OH-PhIP.
Definition
ChEBI: N-hydroxy-PhIP is an imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, hydoxyamino, and phenyl groups, respectively. The active metabolite of the dietary carcinogen PhIP. It has a role as a carcinogenic agent, a mutagen, a genotoxin, a human xenobiotic metabolite, a mouse metabolite, a rat metabolite and a neurotoxin. It is an imidazopyridine and a hydroxylamine. It is functionally related to a PhIP.
Properties of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
| Boiling point: | 421.7±55.0 °C(Predicted) |
| Density | 1.35±0.1 g/cm3(Predicted) |
| pka | 11.70±0.40(Predicted) |
Safety information for 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
Computed Descriptors for 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine
New Products
Paroxetine Impurity G/Paroxetine Related Compound E 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) 1-aminocyclopentane carbonitrile, HCl H-D-TRP(FOR)-OH HCL 9-Mesityl-10-methylacridinium perchlorate 3-Amino-3-(4-fluorophenyl)propanoic acid Benzyl (3R,4S)-3-(2-bromoacetyl)-4-ethylpyrrolidine-1-carboxylate Bisacodyl Related Compound C/Bisacodyl EP Impurity C Levothyroxine Beta Hydroxy Impurity Candesartan EP Impurity-F/Candesartan Cilexetil USP Related Compound F / Candesartan Cilexetil N2-Ethyl Impurity / 2H-N2-Ethyl Candesartan Cilexetil Atorvastatin amide impurity/Atorvastatin EP Impurity F(Calcium Salt) Sumatriptan Succinate USP Related Compound C N-[(1S)-1-benzyl-2-({(1R)-3-methyl-1-[(1S,2S,6R,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.0~2,6~]dec-4-yl]butyl}amino)-2-oxoethyl]-2-pyrazinecarboxamide N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropionamide L-phenylalanine methyl ester hydrochloride 2,2'-(5-Bromomethyl-1,3-phenylene)-di(2-Methylpropionitrile) tri sodium thio phosphate L-phenylalanine, N-(pyrazinyl carbonyl) methyl ester 3-chlorobenzyl cyanide 2-Chloro Benzylcyanide 3,4 Diethoxy Benzylcyanide 4-Bromo Benzylcyanide 3-Hydroxypropionitrile valeronitrileRelated products of tetrahydrofuran
![1H-Imidazo[4,5-b]pyridin-2-amine,1-methyl-](https://img.chemicalbook.in/CAS/GIF/178885-60-4.gif)
![2-Amino-1,6-dimethylimidazo[4,5-b]pyridine](https://img.chemicalbook.in/CAS/GIF/132898-04-5.gif)
![1-Methyl-D3-2-nitro-6-phenylimidazo[4,5-B]pyridine](https://img.chemicalbook.in/CAS/GIF/303173-40-2.gif)
![2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE](https://img.chemicalbook.in/CAS/GIF/105650-23-5.gif)
![1H-Imidazo[4,5-b]pyridin-2-amine(9CI)](https://img.chemicalbook.in/CAS/GIF/132898-03-4.gif)
![1-Methyl-2-nitro-6-phenylimidazo[4,5-B]pyridine](https://img.chemicalbook.in/CAS/GIF/129018-59-3.gif)
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