2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE
- CAS NO.：105650-23-5
- Empirical Formula: C13H12N4
- Molecular Weight: 224.26
- MDL number: MFCD00210745
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-27 17:00:41
![2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE Structural](https://img.chemicalbook.in/CAS/GIF/105650-23-5.gif)
What is 2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE?
Chemical properties
Off-White Solid
The Uses of 2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE
Carcinogen
What are the applications of Application
2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine is a derivitized pyridine compound
Definition
ChEBI: An imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, amino, and phenyl groups, respectively. It is the most abundant of the mutagenic heterocyclic amines found in coo ed meat and fish.
Safety Profile
Confirmed carcinogen with experimental carcinogenic data. Mutation data reported. When heated to decomposition it emits toxic vapors of NOx,.
Carcinogenicity
PhIP is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals and supporting genotoxicity data.
Properties of 2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE
| Melting point: | 300 |
| Boiling point: | 355.66°C (rough estimate) |
| Density | 1.2067 (rough estimate) |
| refractive index | 1.5890 (estimate) |
| storage temp. | Refrigerator |
| solubility | DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 15 mg/ml; Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml |
| form | A crystalline solid |
| pka | 7.72±0.30(Predicted) |
| color | White to light yellow |
| CAS DataBase Reference | 105650-23-5(CAS DataBase Reference) |
| IARC | 2B (Vol. 56) 1993 |
Safety information for 2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H331:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H350:Carcinogenicity H360:Reproductive toxicity |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P311:Call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE
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![1-Methyl-2-nitro-6-phenylimidazo[4,5-B]pyridine](https://img.chemicalbook.in/CAS/GIF/129018-59-3.gif)
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