2-Dimethylaminoethyl chloride hydrochloride
Synonym(s):N-(2-Chloroethyl)dimethylamine hydrochloride;1-Chloro-2-dimethylaminoethane hydrochloride;2-(Dimethylamino)ethyl chloride hydrochloride;Dimethylaminoethyl chloride hydrochloride, N,N-Dimethyl-N-2-chloroethylammonium chloride;N-(2-Chloroethyl)-N,N-dimethylammonium chloride
- CAS NO.:4584-46-7
- Empirical Formula: C4H11Cl2N
- Molecular Weight: 144.04
- MDL number: MFCD00012516
- EINECS: 224-970-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:22:41
What is 2-Dimethylaminoethyl chloride hydrochloride?
Chemical properties
Colorless to beige crystals
The Uses of 2-Dimethylaminoethyl chloride hydrochloride
2-Chloro-N,N-dimethylethylamine hydrochloride (DMC) is used as intermediate for the synthesis of pharmaceuticals (e.g. bephenium hydroxnaphthoate, diltiazem, mepyramine and phenyltoloxamine). Product Data Sheet
The Uses of 2-Dimethylaminoethyl chloride hydrochloride
2-Chloro-N,N-dimethylethylamine is a widely used as a intermediate and starting reagent for organic synthesis. Also acts as Intermediate for the syntheses of bephenium hydroxynaphthoate, diltiazem, mepyramine and phenyltoloxamine.
Definition
ChEBI: 2-dimethylaminoethyl chloride hydrochloride is a hydrochloride obtained by combining 2-dimethylaminoethyl chloride with one molar equivalent of hydrochloric acid. It is a hydrochloride and an organoammonium salt. It contains a 2-dimethylammonioethyl chloride.
Safety Profile
Poison by intraperitoneal and subcutaneous routes. Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of Cland NOx
Properties of 2-Dimethylaminoethyl chloride hydrochloride
| Melting point: | 201-204 °C(lit.) |
| storage temp. | Store below +30°C. |
| solubility | 2000g/l |
| form | Crystalline Powder or Crystals |
| color | White to brown-yellow |
| Water Solubility | 2000 g/L (20 ºC) |
| Sensitive | Hygroscopic |
| BRN | 3591234 |
| Stability: | Hygroscopic |
| CAS DataBase Reference | 4584-46-7(CAS DataBase Reference) |
| EPA Substance Registry System | Ethanamine, 2-chloro-N,N-dimethyl-, hydrochloride (4584-46-7) |
Safety information for 2-Dimethylaminoethyl chloride hydrochloride
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 ![]() Health Hazard GHS08 ![]() Environment GHS09 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H341:Germ cell mutagenicity H373:Specific target organ toxicity, repeated exposure H411:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P273:Avoid release to the environment. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P308+P313:IF exposed or concerned: Get medical advice/attention. |
Computed Descriptors for 2-Dimethylaminoethyl chloride hydrochloride
| InChIKey | LQLJZSJKRYTKTP-UHFFFAOYSA-N |
2-Dimethylaminoethyl chloride hydrochloride manufacturer
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