2-Bromopyridine-5-boronic acid
Synonym(s):2-Bromopyridine-5-boronic acid
- CAS NO.：223463-14-7
- Empirical Formula: C5H5BBrNO2
- Molecular Weight: 201.81
- MDL number: MFCD03411558
- EINECS: 672-028-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 01:24:05
What is 2-Bromopyridine-5-boronic acid?
Chemical properties
Off-white solid
The Uses of 2-Bromopyridine-5-boronic acid
Reactant involved in:
- Iterative cross-coupling reactions for synthesis of non-cytotoxic terpyridines
- The Garlanding approach for synthesis of phenyl-pyridyl scaffolds
- Cyanation for synthesis of aromatic nitriles
- Suzuki-Miyaura cross-coupling with dihalopyridines and dihalobipyridines
- Petasis boronic Mannich reaction
General Description
May contain varying amounts of anhydride
Properties of 2-Bromopyridine-5-boronic acid
| Melting point: | 161-166 °C |
| Boiling point: | 358.2±52.0 °C(Predicted) |
| Density | 1.78±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | soluble in Methanol |
| form | solid |
| pka | 6.62±0.10(Predicted) |
| color | white to off-white |
| BRN | 9119918 |
| CAS DataBase Reference | 223463-14-7(CAS DataBase Reference) |
Safety information for 2-Bromopyridine-5-boronic acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 2-Bromopyridine-5-boronic acid
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