17-OCTADECYNOIC ACID
Synonym(s):17-ODYA;Alkynyl Stearic Acid;Octadec-17-ynoic acid
- CAS NO.：34450-18-5
- Empirical Formula: C18H32O2
- Molecular Weight: 280.45
- MDL number: MFCD00077382
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 03:44:35
What is 17-OCTADECYNOIC ACID?
Description
Alkynyl stearic acid can be used to identify and characterize the post-translational acylation of proteins with powerful Click Chemistry.
The Uses of 17-OCTADECYNOIC ACID
17-ODYA (17-Octadecynoic acid) is a potent suicide inhibitor of LTB4 ω-oxidase.
What are the applications of Application
17-ODYA (17-Octadecynoic acid) is a potent suicide inhibitor of LTB4 ω-oxidase
Definition
ChEBI: Octadec-17-ynoic acid is an acetylenic fatty acid that is octadecanoi acid (stearic acid) which has been doubly dehydrogenated at positions 17 and 18 to give the corresponding alkynoic acid. It has a role as a P450 inhibitor, an EC 1.14.14.94 (leukotriene-B4 20-monooxygenase) inhibitor and an EC 1.14.15.3 (alkane 1-monooxygenase) inhibitor. It is a long-chain fatty acid, an acetylenic fatty acid, a terminal acetylenic compound and a monounsaturated fatty acid.
Biological Activity
Potent suicide inhibitor of LTB 4 ω -hydroxylase.
Biochem/physiol Actions
17-Octadecynoic acid (7-ODYA) is an irreversible inhibitor of cytochrome P450 isozymes, that participates in long-chain fatty acid metabolism.
Storage
Store at -20°C
Properties of 17-OCTADECYNOIC ACID
| Boiling point: | 400.8±18.0 °C(Predicted) |
| Density | 0.922±0.06 g/cm3(Predicted) |
| storage temp. | Store at RT |
| solubility | Soluble to 50 mM in ethanol and to 100 mM in DMSO |
| form | White solid. |
| pka | 4.78±0.10(Predicted) |
| color | White to off-white |
| CAS DataBase Reference | 34450-18-5(CAS DataBase Reference) |
Safety information for 17-OCTADECYNOIC ACID
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 17-OCTADECYNOIC ACID
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![17-OCTADECYNOIC ACID [1-14C]](https://img.chemicalbook.in/StructureFile/ChemBookStructure20/GIF/CB4987491.gif)
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