15-hexadecynoic acid
Synonym(s):15-hexadecynoic acid
- CAS NO.：99208-90-9
- Empirical Formula: C16H28O2
- Molecular Weight: 252.39
- MDL number: MFCD22124928
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:13:02
What is 15-hexadecynoic acid?
Description
Alkynyl palmitic acid can be used to identify and characterize the post-translational S-palmitoylation of proteins with Click Chemistry.
The Uses of 15-hexadecynoic acid
15-hexadecynoic acid is a form of palmitic acid with an ω-terminal alkyne. The terminal alkyne group can be used in linking reactions, known as click chemistry; this chemistry is characterized by high dependability and specificity of the azide-alkyne bioconjugation reactions. The use of palmitic acid alkyne and related lipids in isolating palmitoylated proteins has been described.
The Uses of 15-hexadecynoic acid
Palmitic acid (15-yne) has been used as a component of fatty acid probe stock solution for the optimization of Alk-C16 incorporation onto cellular proteins. It is also suitable for metabolic labeling.
Biochem/physiol Actions
Alkynyl palmitic acid (aPA) is a modified palmitic acid with an ω-terminal alkyne. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents, known as ‘click chemistry′. The click chemistry reactions are rapid, convenient, versatile and regiospecific. They are easy to purify. aPA can be used for isolating palmitoylated proteins.
Properties of 15-hexadecynoic acid
| Melting point: | 59.1°C (estimate) |
| Boiling point: | 409.64°C (rough estimate) |
| Density | 0.9310 (rough estimate) |
| refractive index | 1.4217 (estimate) |
| storage temp. | -20°C |
| solubility | DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS(pH 7.2) (1:5): 0.15 mg/ml |
| form | A crystalline solid |
| color | White to off-white |
Safety information for 15-hexadecynoic acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 15-hexadecynoic acid
New Products
DL-beta-(3-Bromophenyl)alanine 1-Aminocyclopentane carbonitrile (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid N,N CARBONYL DIIMIDAZOLE 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) Benzyl (3R,4S)-3-(2-bromoacetyl)-4-ethylpyrrolidine-1-carboxylate Amlodipine EP Impurity-C Budesonide Impurity-K/Budesonide 21-Acetate (Epimers) Gabapentine Impurity 72 Bicalutamide Impurity-B Betahistine EP Impurity C Carbamazepine EP Impurity G 2,2'-(5-methyl-1,3-phenylene)-di(2-Methylpropionitrile) 4-Fluorothiophenol 1-methyl amino-2,4-dinitro benzene 5-Methyl-1,3-benzenediacetonitrile (R)-BoroLeu-(+)-Pinanediol-CF3COOH 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 3-Hydroxypropionitrile 4-Bromo Benzylcyanide valeronitrile 3,4 Dimethoxy Benzylcyanide 3-chlorobenzyl cyanide 2-Chloro BenzylcyanideRelated products of tetrahydrofuran
You may like
-
Palmitic acid (15-yne) CAS 99208-90-9View Details
99208-90-9 -
110-59-8 valeronitrile 99%View Details
110-59-8 -
93-17-4 99%View Details
93-17-4 -
4-Bromo Benzylcyanide 99%View Details
26451-08-1 -
3-Hydroxypropionitrile 109-78-4 99%View Details
109-78-4 -
1529-41-5 3-chlorobenzyl cyanide 99%View Details
1529-41-5 -
2856-63-5 99%View Details
2856-63-5 -
3,4 Diethoxy Benzylcyanide 99%View Details
27472-21-5