1,2,3,4-Tetrahydrocarbazole
- CAS NO.：942-01-8
- Empirical Formula: C12H13N
- Molecular Weight: 171.24
- MDL number: MFCD00004959
- EINECS: 213-385-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:58:40
What is 1,2,3,4-Tetrahydrocarbazole?
Chemical properties
beige crystalline powder
The Uses of 1,2,3,4-Tetrahydrocarbazole
1,2,3,4-Tetrahydrocarbazole can be used as a starting material to prepare:
- Spiro[cyclopentane-1,2′-indolin-3′-one] by photooxygenation.
- 9-Acyl-1,2,3,4-tetrahydrocarbazoles by N-acylation reactions.
- Carbazole via palladium-catalyzed asymmetric hydrogenation reaction.
The Uses of 1,2,3,4-Tetrahydrocarbazole
It finds its application as a pharmaceutical intermediate and in the synthesis of aspidospermidine alkaloids.
Synthesis Reference(s)
Chemical and Pharmaceutical Bulletin, 14, p. 934, 1966 DOI: 10.1248/cpb.14.934
Tetrahedron Letters, 26, p. 161, 1985 DOI: 10.1016/S0040-4039(00)61869-5
Properties of 1,2,3,4-Tetrahydrocarbazole
| Melting point: | 118-120 °C (lit.) |
| Boiling point: | 325-330 °C (lit.) |
| Density | 1.1459 (rough estimate) |
| refractive index | 1.6544 (estimate) |
| Flash point: | 325-330°C |
| storage temp. | Sealed in dry,Room Temperature |
| form | powder to crystal |
| pka | 17.84±0.20(Predicted) |
| color | White to Orange to Green |
| Water Solubility | Insoluble in water. Solubility in methanol (almost transparency). |
| BRN | 133771 |
| CAS DataBase Reference | 942-01-8(CAS DataBase Reference) |
| NIST Chemistry Reference | 1H-Carbazole, 2,3,4,9-tetrahydro-(942-01-8) |
Safety information for 1,2,3,4-Tetrahydrocarbazole
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1,2,3,4-Tetrahydrocarbazole
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