1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
- CAS NO.：28289-54-5
- Empirical Formula: C12H15N
- Molecular Weight: 173.25
- MDL number: MFCD00006120
- EINECS: 248-939-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:55:36
What is 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine?
Chemical properties
Light Yellow Solid
The Uses of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine is a dopaminergic neurotoxin that reportedly causes a severe and irreversible Parkinsonian condition in humans and monkeys.
What are the applications of Application
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine, free base is a dopaminergic neurotoxin
Definition
ChEBI: A tetrahydropyridine that is 1,2,3,6-tetrahydropyridine substituted by a methyl group at position 1 and a phenyl group at position 4.
Metabolic pathway
N-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in a rat pheochromocytoma cell line is oxidized to give the N-methyl-4-phenylpyridinium ion.
Properties of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
| Melting point: | aprox. 36°C |
| Boiling point: | 128-132 °C12 mm Hg(lit.) |
| Density | 1.001±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform (Slightly), Dichloromethane (Slightly), Ethyl Acetate (Slightly) |
| pka | 8.66±0.40(Predicted) |
| form | Solid |
| color | Pale Yellow to Light Yellow |
| Merck | 13,6319 |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
Safety information for 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Computed Descriptors for 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
New Products
9-Mesityl-10-methylacridinium perchlorate Sulfapyridine Fmoc-OSu (R)-(-)-2-Amino-1-propanol Cyclobutanone 5-bromo-4-fluoro-2-nitrobenzaldehyde 4 pentyn 1 ol N-Vinylformamide Phenethyl cinnamate Pyrrolo[1,2-a]pyrimidine-6-carboxylic acid, 4,6,7,8-tetrahydro-4-oxo-, sodium salt (1:1), (6S) Ethyl 3-phenylpropanoate β-Bromostyrene Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 5-Bromo-1-Pentyne 1-(2-Methyl-5-nitrophenyl)guanidine Nitrate Methyl trans-4-Aminocyclohexanecarboxylate Hydrochloride N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide 4-Nitrobenzotrifluoride 2-Pentyn-1-oLRelated products of tetrahydrofuran
![METHYL-4-PHENYL 1,2,3,6-TETRAHYDROPYRIDINE, 1-, [METHYL-14C]](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB0130619.gif)
![METHYL-4-PHENYL 1,2,3,6-TETRAHYDROPYRIDINE, 1-, [METHYL-3H]](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB1120901.gif)
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