1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE
- CAS NO.：28289-54-5
- Empirical Formula: C12H15N
- Molecular Weight: 173.25
- MDL number: MFCD00006120
- EINECS: 248-939-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 05:08:46
What is 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE?
Chemical properties
Light Yellow Solid
The Uses of 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine is a dopaminergic neurotoxin that reportedly causes a severe and irreversible Parkinsonian condition in humans and monkeys.
What are the applications of Application
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine, free base is a dopaminergic neurotoxin
Definition
ChEBI: A tetrahydropyridine that is 1,2,3,6-tetrahydropyridine substituted by a methyl group at position 1 and a phenyl group at position 4.
Metabolic pathway
N-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in a rat pheochromocytoma cell line is oxidized to give the N-methyl-4-phenylpyridinium ion.
Properties of 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE
| Melting point: | aprox. 36°C |
| Boiling point: | 128-132 °C12 mm Hg(lit.) |
| Density | 1.001±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform (Slightly), Dichloromethane (Slightly), Ethyl Acetate (Slightly) |
| pka | 8.66±0.40(Predicted) |
| form | Solid |
| color | Pale Yellow to Light Yellow |
| Merck | 13,6319 |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
Safety information for 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE
Computed Descriptors for 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE
New Products
1-(4-methoxyphenyl)-4-(4-Nitrophenyl)Piperazine (IT-1) 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-One Dibenzo[b,f][1,4]thiazepin-11(10H)-one Cis-Tosylate Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) 1-Benzhydrylazetane-3-carbonitrile 8-oxa-1,3-diazaspiro[4.5]decane-2,4-dione (±)-amino(2-fluorophenyl)acetic acid 2-(2-Chlorophenyl)glycine AMINO-(3-CHLORO-PHENYL)-ACETIC ACID 2'-Fluoroacetophenone METHANOL-D1(OD) N-ETHYL-D5-AMINE HYDROCHLORIDE BENZOIC ACID-D CHLOROFORM-D BENZENE-D6 TOLUENE-D3 2-Hydroxybutanenitrile 1-Benzylindolin-2-one Ethyl 2-bromo-3-oxobutanoate 4-(3-chloropropyl)morpholine 1-Benzylindoline-2,3-dione 3-Oxocyclobutanecarboxylic acid 1-(3-Chlorophenyl)piperazine hydrochlorideRelated products of tetrahydrofuran
![METHYL-4-PHENYL 1,2,3,6-TETRAHYDROPYRIDINE, 1-, [METHYL-14C]](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB0130619.gif)
![METHYL-4-PHENYL 1,2,3,6-TETRAHYDROPYRIDINE, 1-, [METHYL-3H]](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB1120901.gif)
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