Setiptiline
- CAS NO.：57262-94-9
- Empirical Formula: C19H19N
- Molecular Weight: 261.36
- MDL number: MFCD00868385
- EINECS: 260-653-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 01:16:13
What is Setiptiline?
Description
Setiptiline is a mianserin analog reportedly useful in the treatment of depression with a favorable side-effect profile. It is a potent antagonist of alpha-receptors, with greater affinity at alpha, than alpha, sites, as well as an inhibitor of central serotonin receptors.
Originator
Organon (Netherlands)
The Uses of Setiptiline
Setiptiline is a tetracyclic antidepressant. Setiptiline acts as a noradrenergic and specific serotonergic antidepressant (NaSSA).
Definition
ChEBI: Setiptiline is a tetracyclic antidepressant that is 2,3,4,9-tetrahydro-1H-dibenzo[3,4:6,7]cyclohepta[1,2-c]pyridine carrying a methyl group at position 2. Its maleate salt is used for the treatment of depression in Japan. It has a role as an alpha-adrenergic antagonist and a serotonergic antagonist. It is a tetracyclic antidepressant and a tertiary amino compound. It is a conjugate base of a setiptiline(1+).
brand name
Tecipul
Properties of Setiptiline
| Melting point: | >120°C (dec.) |
| Boiling point: | 421.7±34.0 °C(Predicted) |
| Density | 1.15 |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 8.34±0.20(Predicted) |
| color | White to Light Yellow |
Safety information for Setiptiline
Computed Descriptors for Setiptiline
New Products
N-Carbethoxy-4-piperidone 1-Aminocyclopentane carbonitrile Tetrabutylammonium perchlorate N,O-Dimethylhydroxylamine hydrochloride (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 2-Amino-5-bromo-4-(trifluoromethyl)pyridine N-Vinylformamide 4 pentyn 1 ol Phenethyl cinnamate Dipropyl disulfide Ethyl 3-phenylpropanoate β-Bromostyrene Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 5-Bromo-1-Pentyne 1-(2-Methyl-5-nitrophenyl)guanidine Nitrate Methyl trans-4-Aminocyclohexanecarboxylate Hydrochloride N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide 2-Pentyn-1-oL 4-NitrobenzotrifluorideRelated products of tetrahydrofuran
![5H-dibenzo[a,d]cycloheptene](https://img.chemicalbook.in/CAS/GIF/256-81-5.gif)
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