1-(4-Chlorophenyl)piperazine
- CAS NO.：38212-33-8
- Empirical Formula: C10H13ClN2
- Molecular Weight: 196.68
- MDL number: MFCD00044823
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:21:29
What is 1-(4-Chlorophenyl)piperazine?
Chemical properties
light yellow crystalline powder
The Uses of 1-(4-Chlorophenyl)piperazine
1-(4-Chlorophenyl)piperazine is used as a 5-HT-1 serotonin receptor agonist. It is also used as a pharmaceutical intermediate.
Properties of 1-(4-Chlorophenyl)piperazine
| Melting point: | 76-79 °C |
| Boiling point: | 113°C/0.27mm |
| Density | 1.1428 (rough estimate) |
| refractive index | 1.5749 (estimate) |
| solubility | DMF: 30 mg/ml; DMF:PBS(pH7.2) (1:2): 0.33 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; Methanol: 1 mg/ml |
| pka | 8.88±0.10(Predicted) |
| form | Solid |
| Water Solubility | It is soluble in water. |
| BRN | 150981 |
| CAS DataBase Reference | 38212-33-8(CAS DataBase Reference) |
Safety information for 1-(4-Chlorophenyl)piperazine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1-(4-Chlorophenyl)piperazine
| InChIKey | UNEIHNMKASENIG-UHFFFAOYSA-N |
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