Chlorodimethylphenylsilane
Synonym(s):Dimethylphenylchlorosilane;Dimethylphenylsilylchloride;DMPSCl;Phenyldimethylchlorosilane
- CAS NO.：768-33-2
- Empirical Formula: C8H11ClSi
- Molecular Weight: 170.71
- MDL number: MFCD00000499
- EINECS: 212-193-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:14:08
What is Chlorodimethylphenylsilane?
Chemical properties
clear colorless to light yellow liquid
The Uses of Chlorodimethylphenylsilane
Chlorodimethylphenylsilane is used in the synthesis of enantioenriched allenylsilanes through an ortho-ester Claisen rearrangement of chiral and silylpropargylic alcohols.
Purification Methods
Fractionate it through a 1.5 x 18inch column packed with stainless steel helices, or a spinning band column. [Daudt & Hyde J Am Chem Soc 74 386 1952, Lewis et al. J Am Chem Soc 70 1115 1948, Eaborn J Chem Soc 494 1953.] It is used for standardising MeLi or MeMgBr which form Me3PhSi which is estimated by GC. [Maienthal et al. J Am Chem Soc 76 6392 1954, House & Respess J Organomet Chem 4 95 1965, Beilstein 16 IV 1475.] TOXIC and MOISTURE SENSITIVE.
Properties of Chlorodimethylphenylsilane
| Melting point: | <0°C |
| Boiling point: | 194-198 °C |
| Density | 1.017 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 143 °F |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Miscible with tetrahydrofuran, ether and hexane. |
| form | clear liquid |
| color | Colorless to Light yellow |
| Specific Gravity | 1.017 |
| Water Solubility | MAY DECOMPOSE |
| Sensitive | Moisture Sensitive |
| Hydrolytic Sensitivity | 8: reacts rapidly with moisture, water, protic solvents |
| BRN | 606292 |
| CAS DataBase Reference | 768-33-2(CAS DataBase Reference) |
| NIST Chemistry Reference | Silane, chlorodimethylphenyl-(768-33-2) |
| EPA Substance Registry System | Silane, chlorodimethylphenyl- (768-33-2) |
Safety information for Chlorodimethylphenylsilane
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for Chlorodimethylphenylsilane
| InChIKey | KWYZNESIGBQHJK-UHFFFAOYSA-N |
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