Chlorodimethylphenylsilane

Synonym(s):Dimethylphenylchlorosilane;Dimethylphenylsilylchloride;DMPSCl;Phenyldimethylchlorosilane

CAS NO.：768-33-2
Empirical Formula: C8H11ClSi
Molecular Weight: 170.71
MDL number: MFCD00000499
EINECS: 212-193-0
SAFETY DATA SHEET (SDS)
Update Date: 2025-06-12 17:38:40

What is Chlorodimethylphenylsilane?

Chemical properties

clear colorless to light yellow liquid

The Uses of Chlorodimethylphenylsilane

Chlorodimethylphenylsilane is used in the synthesis of enantioenriched allenylsilanes through an ortho-ester Claisen rearrangement of chiral and silylpropargylic alcohols.

Purification Methods

Fractionate it through a 1.5 x 18inch column packed with stainless steel helices, or a spinning band column. [Daudt & Hyde J Am Chem Soc 74 386 1952, Lewis et al. J Am Chem Soc 70 1115 1948, Eaborn J Chem Soc 494 1953.] It is used for standardising MeLi or MeMgBr which form Me3PhSi which is estimated by GC. [Maienthal et al. J Am Chem Soc 76 6392 1954, House & Respess J Organomet Chem 4 95 1965, Beilstein 16 IV 1475.] TOXIC and MOISTURE SENSITIVE.

Properties of Chlorodimethylphenylsilane

Melting point:	<0°C
Boiling point:	194-198 °C
Density	1.017 g/mL at 25 °C(lit.)
refractive index	n20/D 1.509(lit.)
Flash point:	143 °F
storage temp.	Inert atmosphere,Room Temperature
solubility	Miscible with tetrahydrofuran, ether and hexane.
form	clear liquid
color	Colorless to Light yellow
Specific Gravity	1.017
Water Solubility	MAY DECOMPOSE
Sensitive	Moisture Sensitive
Hydrolytic Sensitivity	8: reacts rapidly with moisture, water, protic solvents
BRN	606292
CAS DataBase Reference	768-33-2(CAS DataBase Reference)
NIST Chemistry Reference	Silane, chlorodimethylphenyl-(768-33-2)
EPA Substance Registry System	Silane, chlorodimethylphenyl- (768-33-2)

Safety information for Chlorodimethylphenylsilane

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05
GHS Hazard Statements	H314:Skin corrosion/irritation
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.