1-[3-(3,4-Methylenedioxyphenoxy)propyl]-4-phenyl-piperazine maleate

CAS NO.：82900-57-0
Empirical Formula: C20H24N2O3
Molecular Weight: 340.42
MDL number: MFCD00209933
SAFETY DATA SHEET (SDS)
Update Date: 2026-09-12 18:54:58

What is 1-[3-(3,4-Methylenedioxyphenoxy)propyl]-4-phenyl-piperazine maleate?

The Uses of 1-[3-(3,4-Methylenedioxyphenoxy)propyl]-4-phenyl-piperazine maleate

BP 554 Maleate was used to study the methods for the classification and diagnosis of scoliosis.

Definition

ChEBI: 1-[3-(1,3-benzodioxol-5-yloxy)propyl]-4-phenylpiperazine is a member of piperazines.

Biological Activity

Selective 5-HT 1A agonist.

References

[1]. matsuda t, seong yh, aono h, et al. agonist activity of a novel compound, 1-[3-(3,4-methylenedioxyphenoxy)propyl]-4-phenyl piperazine (bp-554), at central 5-ht1a receptors. eur j pharmacol, 1989, 170(1-2): 75-82.
[2]. galter d, unsicker k. sequential activation of the 5-ht1(a) serotonin receptor and trkb induces the serotonergic neuronal phenotype. mol cell neurosci, 2000, 15(5): 446-455.
[3]. rauch a, rainer g, logothetis nk. the effect of a serotonin-induced dissociation between spiking and perisynaptic activity on bold functional mri. proc natl acad sci u s a, 2008, 105(18): 6759-6764.

Properties of 1-[3-(3,4-Methylenedioxyphenoxy)propyl]-4-phenyl-piperazine maleate

Boiling point:	496.9±45.0 °C(Predicted)
Density	1.188±0.06 g/cm3(Predicted)
storage temp.	Store at RT
solubility	<45.65mg/ml in DMSO
form	solid
pka	7.42±0.10(Predicted)
color	Off-white

Safety information for 1-[3-(3,4-Methylenedioxyphenoxy)propyl]-4-phenyl-piperazine maleate

Computed Descriptors for 1-[3-(3,4-Methylenedioxyphenoxy)propyl]-4-phenyl-piperazine maleate

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1-[3-(3,4-METHYLENEDIOXYPHENOXY)PROPYL]-4-PHENYL-PIPERAZINE MALEATE