1-Piperazinepropanol
Synonym(s):3-(1-Piperazinyl)-1-propanol;3-(1-Piperazinyl)propanol;4-(3-Hydroxypropyl)piperazine;N-(3-Hydroxypropyl)piperazine;1-(3-Hydroxy-1-propyl)piperazine
- CAS NO.：5317-32-8
- Empirical Formula: C7H16N2O
- Molecular Weight: 144.21
- MDL number: MFCD00023132
- EINECS: 226-176-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-14 15:27:00
What is 1-Piperazinepropanol?
Chemical properties
White powder or crystal
The Uses of 1-Piperazinepropanol
Reactant for preparation of biologically active molecules:
- Preparation of chloropyridazine piperazines as human rhinovirus (HRV-3) inhibitors
- Synthesis of arylbenzoylpyrrolidine derivatives and their Hsp90 inhibitory activity
- Synthesis of pyrrolothienopyrazines as novel serotonin-4 receptors antagonists
- Preparation of carbamate-functionalized 2,6-disubstituted N-(arylsulfonyl) piperidines as conformationally restricted and orally active γ-secretase inhibitors
Properties of 1-Piperazinepropanol
| Melting point: | 49-53 °C (lit.) |
| Boiling point: | 94-96°C/1.8mm |
| Density | 0.993±0.06 g/cm3(Predicted) |
| Flash point: | >230 °F |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| pka | 15.10±0.10(Predicted) |
| color | Colourless ified liquid |
| CAS DataBase Reference | 5317-32-8(CAS DataBase Reference) |
Safety information for 1-Piperazinepropanol
| Signal word | Warning |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 1-Piperazinepropanol
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