1397-89-3

Product Name: Amphotericin B

Formula: C47H73NO17

Synonyms: Amphotericin;Amphotericin B;Amphotericin B from Streptomyces sp.;Fungizone

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CHEMICAL AND PHYSICAL PROPERTIES SAFETY INFORMATION COMPUTED DESCRIPTORS PRODUCT INTRODUCTION RELATED SUPPLIERS

CHEMICAL AND PHYSICAL PROPERTIES

Physical Description	Amphotericin b is a bright yellow powder. (NTP, 1992)
Color/Form	Deep yellow prisms or needles from n,n-dimethylformamide
Odor	ODORLESS OR PRACTICALLY SO
Melting Point	greater than 338 °F (decomposes) (NTP, 1992)
Solubility	less than 1 mg/mL at 70 °F (NTP, 1992)
LogP	0.8
Stability/Shelf Life	Solids and solutions appear stable for long periods between pH 4 and 10 when stored at moderate temperature out of light and air.
Optical Rotation	Specific optical rotation at 24 °C/D: +333 deg (acidic N,N-dimethylformamide); -33.6 deg (0.1 N methanolic hydrochloric acid)
Decomposition	When heated to decomposition it emits toxic fumes of /nitrogen oxides/.

Signal word	Danger
Pictogram(s)	Health Hazard GHS08
GHS Hazard Statements	H372:Specific target organ toxicity, repeated exposure
Precautionary Statement Codes	P260:Do not breathe dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P314:Get medical advice/attention if you feel unwell. P501:Dispose of contents/container to..…

Molecular Weight	924.1 g/mol
XLogP3	0
Hydrogen Bond Donor Count	12
Hydrogen Bond Acceptor Count	18
Rotatable Bond Count	3
Exact Mass	923.48784986 g/mol
Monoisotopic Mass	923.48784986 g/mol
Topological Polar Surface Area	320 Å²
Heavy Atom Count	65
Formal Charge	0
Complexity	1670
Isotope Atom Count	0
Defined Atom Stereocenter Count	19
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	7
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes