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HomeProduct name listZindotrine

Zindotrine

Zindotrine Structural

What is Zindotrine?

Originator

Zindotrine,Dow Chemical Co., USA

The Uses of Zindotrine

Bronchodilator.

Manufacturing Process

A mixture of 20.0 g of 3-hydrazino-4-methyl-6-piperidinopyridazine in 100 ml of aqueous 99% formic acid was heated at the boiling temperature under reflux for 3 h and then evaporated to dryness. The residue, containing 8- methyl-6-piperidino-s-triazolo[4,3-b]pyridazine formate was taken up in excess aqueous sodium carbonate and extracted with chloroform. After evaporation of the chloroform solvent the 8-methyl-6-piperidino-s- triazolo[4,3-b]pyridazine was crystallized from ethyl acetate. Yield 4.4 g, melting point 118-120°C.

Therapeutic Function

Bronchodilator

Properties of Zindotrine

Density  1.36±0.1 g/cm3(Predicted)
pka 4.80±0.30(Predicted)

Safety information for Zindotrine

Computed Descriptors for Zindotrine

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