XANTHURENIC ACID
Synonym(s):4,8-Dihydroxyquinaldic acid;4,8-Dihydroxyquinoline-2-carboxylic acid
- CAS NO.:59-00-7
- Empirical Formula: C10H7NO4
- Molecular Weight: 205.17
- MDL number: MFCD00006754
- EINECS: 200-410-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 02:20:04
What is XANTHURENIC ACID?
Chemical properties
ochre powder
The Uses of XANTHURENIC ACID
Xanthurenic acid can be used as a substrate for the synthesis of:
- Silica-gel functionalized xanthurenic acid (4, 8-dihydroxyquinoline-2-carboxylic acid) as an adsorbent for metal ions.
- N, N′-bis-((8-hydroxy-7-quinolinyl)methyl)-1,10-diaza-18-crown-6 ethers as fluorescent sensors of magnesium in living cells via one-pot Mannich reaction.
- Poly-xanthurenic acid (poly-Xa) for biosensing applications.
The Uses of XANTHURENIC ACID
Excreted by pyridoxine-deficient animals after the ingestion of tryptophan.
The Uses of XANTHURENIC ACID
caspase activator, guanylyl cyclase stimulant
What are the applications of Application
Xanthurenic acid is a potent activator of group II mGluRs
Definition
ChEBI: A quinolinemonocarboxylic acid that is quinoline-2-carboxylic acid substituted by hydroxy groups at C-4 and C-8.
Storage
Room temperature
Purification Methods
It is precipitated by the addition of 2N formic acid to its solution in hot 2M ammonia (charcoal). The solid is filtered off, dried in a vacuum at ~80o in the dark. UV (H2O) has nm ( M-1cm-1): 243 (30,000) and 342 (6,500). The methyl ester has m 262o (from MeOH). It forms Cu2+, Zn2+, Fe2+ and Fe3+ salts. [Beilstein 22 III/IV 2513.]
Properties of XANTHURENIC ACID
| Melting point: | 297-298 °C (dec.)(lit.) |
| Boiling point: | 343.83°C (rough estimate) |
| Density | 1.3849 (rough estimate) |
| refractive index | 1.5600 (estimate) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | DMSO (Slightly, Heated), Water (Slightly, Heated) |
| form | Powder |
| pka | 1.20±0.30(Predicted) |
| color | Ochre |
| Merck | 14,10068 |
| BRN | 185954 |
| CAS DataBase Reference | 59-00-7(CAS DataBase Reference) |
Safety information for XANTHURENIC ACID
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for XANTHURENIC ACID
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