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HomeProduct name listVU0238441

VU0238441

VU0238441 Structural

What is VU0238441?

Biological Activity

VU0238441 is a positive allosteric modulator (PAM) of pan-muscarinic acetylcholine receptor (mAChR) with EC50 values of 2.1 μM, 2.2 μM, 2.8 μM, 3.2 μM and > 2.1 μM, 2.2 μM, 2.8 μM, 3.2 μM and > for M5, M3, M2, M1 and M4, respectively 10 μM.

in vitro

VU0238441 is an analogue of VU0119498.

Properties of VU0238441

Boiling point: 441.7±55.0 °C(Predicted)
Density  1.500±0.06 g/cm3(Predicted)
storage temp.  Sealed in dry,Room Temperature
solubility  DMSO: 125 mg/mL (367.97 mM)
pka -3?+-.0.20(Predicted)
form  Solid
color  Brown to red

Safety information for VU0238441

Computed Descriptors for VU0238441

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