vomicine
- CAS NO.：125-15-5
- Empirical Formula: C22H24N2O4
- Molecular Weight: 380.44
- MDL number: MFCD00033661
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-05 14:33:18
What is vomicine?
Description
Schaefer has obtained this base from old seeds of Strychnos Nux-vomica which had deteriorated where is occurs to the extent of about 0.1 per cent. It forms colourless crystals from EtOH which become yellow on exposure to light. With H2S04 it gives a colourless solution that becomes green on the addition of potassium dichromate. From the available evidence it seems likely that it is not a true alkaloid but a decomposition product of either strychnine or brucine.
The Uses of vomicine
Vomicine is an antiplasmoidal alkaloid extracted from the stem bark of Strychnos malacoclados and is useful against malaria.
Definition
ChEBI: Vomicine is a member of carbazoles.
References
Schaefer.,J. Amer. Pharm. Assoc., 3,1677 (1914)
Properties of vomicine
| Melting point: | 286-290℃ (dec.) |
| Boiling point: | 508.07°C (rough estimate) |
| alpha | D22 +80° (c = 0.5 in alc) |
| Density | 1.44±0.1 g/cm3 (20 ºC 760 Torr) |
| refractive index | 1.6500 (estimate) |
| pka | 9.18±0.20(Predicted) |
| form | Solid |
| color | White to off-white |
Safety information for vomicine
Computed Descriptors for vomicine
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