Vatalanib base
- CAS NO.：212141-54-3
- Empirical Formula: C20H15ClN4
- Molecular Weight: 346.81
- MDL number: MFCD08458963
- EINECS: 202-303-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-27 17:00:41
What is Vatalanib base?
The Uses of Vatalanib base
Vatalanib (PTK787) is an inhibitor of VEGFR2/KDR, Flt-1 and c-Kit with IC50 of 37 nM, 77 nM and 730 nM, respectively.
The Uses of Vatalanib base
anti-viral
Definition
ChEBI: A member of the class of phthalazines that is phthalazine in which the hydrogens at positions 1 and 4have been replaced by a p-chlorophenylamino group and a pyridin-4-ylmethyl group, respectively. It is a multi-targeted tyrosine kinase inhibit r for all isoforms of VEGFR, PDGFR and c-Kit.
Properties of Vatalanib base
| Melting point: | 209-212° |
| Boiling point: | 587.8±50.0 °C(Predicted) |
| Density | 1.330±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C(protect from light) |
| solubility | ≥16.85 mg/mL in DMSO; ≥3.0125 mg/mL in EtOH with gentle warming and ultrasonic; ≥32.53 mg/mL in H2O with gentle warming and ultrasonic |
| form | solid |
| pka | 5.46±0.10(Predicted) |
| color | Light yellow to yellow |
Safety information for Vatalanib base
Computed Descriptors for Vatalanib base
Vatalanib base manufacturer
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