Tyr-Ile-Gly-Ser-Arg
Synonym(s):Laminin Fragment 929-933
- CAS NO.：110590-64-2
- Empirical Formula: C26H42N8O8
- Molecular Weight: 594.66
- MDL number: MFCD00076472
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:48:19
What is Tyr-Ile-Gly-Ser-Arg?
The Uses of Tyr-Ile-Gly-Ser-Arg
Tyr-Ile-Gly-Ser-Arg (YIGSR) can be used at the interface between the conjugated polymer and the tissue for the engineering of tissue interface. The product can also be used to study the role of integrins β1, α6, and α3 in promoting type II epithelial differentiation during lung maturation in the fetus.
Biochem/physiol Actions
Tyr-Ile-Gly-Ser-Arg (YIGSR) is a pentapeptide of the protein laminin that reduces the lung colony formation in mice administered with melanoma cells as well as can block the invasiveness of the cells in vitro. It inhibits the increased expression of endothelial nitric-oxide synthase in primary porcine aortic endothelial cells.
Properties of Tyr-Ile-Gly-Ser-Arg
| Melting point: | 126-129 °C |
| Density | 1.44±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | H2O: soluble1mg/mL, clear, colorless |
| form | Solid |
| pka | 3.23±0.10(Predicted) |
Safety information for Tyr-Ile-Gly-Ser-Arg
Computed Descriptors for Tyr-Ile-Gly-Ser-Arg
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![GLYCOGEN SYNTHASE KINASE 3 BETA (PTYR 216) (210-220) [MUS MUSCULUS]/[RATTUS NORVEGICUS]](https://img.chemicalbook.in/StructureFile/ChemBookStructure9/GIF/CB0413813.gif)
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