trimethylcolchicinic acid methyl ether
- CAS NO.：3476-50-4
- Empirical Formula: C20H23NO5
- Molecular Weight: 357.4
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-27 23:06:59
What is trimethylcolchicinic acid methyl ether?
Chemical properties
Yellow Solid
The Uses of trimethylcolchicinic acid methyl ether
An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.
What are the applications of Application
N-Deacetylcolchicine is it binds to tubulin thereby preventing its polymerization
Definition
ChEBI: Deacetylcolchicine is a carbotricyclic compound, an alkaloid and a member of acetamides.
Properties of trimethylcolchicinic acid methyl ether
| Boiling point: | 490.03°C (rough estimate) |
| Density | 1.2532 (rough estimate) |
| refractive index | 1.5614 (estimate) |
| storage temp. | -20°C Freezer, Under Inert Atmosphere |
| solubility | DMSO: 25mg/mL; Ethanol: 25mg/mL |
| form | A crystalline solid |
| pka | 8.62±0.40(Predicted) |
Safety information for trimethylcolchicinic acid methyl ether
Computed Descriptors for trimethylcolchicinic acid methyl ether
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