COLCHICOSIDE
- CAS NO.：477-29-2
- Empirical Formula: C27H33NO11
- Molecular Weight: 547.554
- MDL number: MFCD01736974
- EINECS: 207-513-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-10-29 15:43:00
What is COLCHICOSIDE?
Chemical properties
Pale Yellow Solid
The Uses of COLCHICOSIDE
A significantly toxic Colchicine analog with no anti-inflammatory properties.
Definition
ChEBI: Colchicoside is a carbotricyclic compound, an alkaloid and a member of acetamides.
Purification Methods
Purify colchicoside by chromatography through alumina and eluting with CHCl3, then recrystallising from Me2CO, m 275-280o (after releasing solvent at 180o). It also crystallises from EtOH; see colchicine. The tetraacetate has m 175-177o, [] D 15 -57o (c 1, CHCl3). [Bellet et al. Ann Pharm Fr 10 241 1952, Chem Abstr 47 3323 1953, Beilstein 14 IV 946 for colchicine.]
Properties of COLCHICOSIDE
| Melting point: | 194-197°C |
| Boiling point: | 620.17°C (rough estimate) |
| Density | 1.3430 (rough estimate) |
| refractive index | 1.6400 (estimate) |
| storage temp. | Refrigerator |
| solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; PBS (pH 7.2): 10 mg/ml |
| form | A crystalline solid |
| pka | 12.74±0.70(Predicted) |
| color | Light yellow to yellow |
Safety information for COLCHICOSIDE
Computed Descriptors for COLCHICOSIDE
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