COLCHICOSIDE
- CAS NO.:477-29-2
- Empirical Formula: C27H33NO11
- Molecular Weight: 547.55
- MDL number: MFCD01736974
- EINECS: 207-513-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 06:15:51
What is COLCHICOSIDE?
Chemical properties
Pale Yellow Solid
The Uses of COLCHICOSIDE
A significantly toxic Colchicine analog with no anti-inflammatory properties.
Definition
ChEBI: Colchicoside is a carbotricyclic compound, an alkaloid and a member of acetamides.
Purification Methods
Purify colchicoside by chromatography through alumina and eluting with CHCl3, then recrystallising from Me2CO, m 275-280o (after releasing solvent at 180o). It also crystallises from EtOH; see colchicine. The tetraacetate has m 175-177o, [] D 15 -57o (c 1, CHCl3). [Bellet et al. Ann Pharm Fr 10 241 1952, Chem Abstr 47 3323 1953, Beilstein 14 IV 946 for colchicine.]
Properties of COLCHICOSIDE
| Melting point: | 194-197°C |
| Boiling point: | 620.17°C (rough estimate) |
| Density | 1.3430 (rough estimate) |
| refractive index | 1.6400 (estimate) |
| storage temp. | Refrigerator |
| solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; PBS (pH 7.2): 10 mg/ml |
| form | A crystalline solid |
| pka | 12.74±0.70(Predicted) |
| color | Light yellow to yellow |
Safety information for COLCHICOSIDE
Computed Descriptors for COLCHICOSIDE
New Products
Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) Cis-Tosylate 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-One Dibenzo[b,f][1,4]thiazepin-11(10H)-one 1-(4-methoxyphenyl)-4-(4-Nitrophenyl)Piperazine (IT-1) 1-aminocyclobutanecarbonitrile hydrochloride 4-(FMOC-AMINO)-TETRAHYDROPYRAN-4-CARBOXYLIC ACID 1-Aminocyclobutanecarboxylic Acid Hydrochloride AMINO(2-BROMOPHENYL)ACETIC ACID 3-Oxocyclobutanecarboxylic acid 6-BROMOTETRAZOLO[1,5-A]PYRIDINE METHANE-D3-SULFONYL CHLORIDE N-ETHYL-D5-AMINE HYDROCHLORIDE BENZOIC ACID-D TERTIARY BUTANOL-D9 CHLOROFORM-D TOLUENE-D3 2-Amino-5-bromopyridine 2-(2-Bromophenyl)ethanol Boc-D-Glu(OMe)-OMe Ethyl 4-hydroxy-3-oxobutanoate Dimethyl (2S)-2-((tert-butoxycarbonyl)amino)-4-(cyanomethyl)pentanedioate 3-tert-Butyl-5-bromobenzaldehyde 4'-(Methylmercapto)-acetophrnononeRelated products of tetrahydrofuran








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