Trifluoroacetamidine
- CAS NO.：354-37-0
- Empirical Formula: C2H3F3N2
- Molecular Weight: 112.05
- MDL number: MFCD00041545
- EINECS: 670-531-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-23 18:22:18
What is Trifluoroacetamidine?
Chemical properties
Colorless liquid
The Uses of Trifluoroacetamidine
Trifluoroacetamidine is used as probe for determination of membrane potential and extra/intracellular volume of erythrocytes by fluorine-19 NMR studies. It is a reagent used as protected ammonia equivalent.
Synthesis
Trifluoroacetamidine is a vital chemical intermediate with a wide range of applications. A preparation method comprises the following steps: trifluoroacetamide is used as raw materials, polyphosphoric acid is selected as solvents under the effect of phosphorus pentoxide as dehydrating agents, and trifluoroacetonitrile can be fast prepared through a dehydration reaction. The generated trifluoroacetonitrile gas is introduced into a liquid ammonia kettle after being cooled, and the trifluoroacetamidine can be prepared.
Properties of Trifluoroacetamidine
| Boiling point: | 35-37°C 11mm |
| Density | 1.45 |
| refractive index | 1.3801 |
| Flash point: | 35-37°C/11mm |
| storage temp. | Store below -20C |
| pka | 6.07±0.40(Predicted) |
| color | Clear, yellow |
| Water Solubility | Fully miscible in water. |
| Sensitive | Moisture Sensitive |
| BRN | 605978 |
| InChI | InChI=1S/C2H3F3N2/c3-2(4,5)1(6)7/h(H3,6,7) |
| CAS DataBase Reference | 354-37-0(CAS DataBase Reference) |
Safety information for Trifluoroacetamidine
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation H318:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for Trifluoroacetamidine
| InChIKey | NITMACBPVVUGOJ-UHFFFAOYSA-N |
| SMILES | C(N)(=N)C(F)(F)F |
New Products
2-Ethoxyphenol Methyl 2-methoxy-5-sulfamoylbenzoate Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate 3,6-Dichloropyridazine 3,6-Dichloro-4-Isopropylpyridazine 2-[(2-Ethoxyphenoxy)methyl]oxirane m-Tolualdehyde p-Anisaldehyde 2-Bromobenzaldehyde 4-Fluorobenzaldehyde 1-Propyl-4-piperidone 3-Amino-3-(3-fluorophenyl)propanoic acid 6-Methyl-2-pyridinemethanol 2-Pyridinecarboxaldehdye tert-Butyl ((1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate 1-Indanone 2-Chloromethyl-6-methyl-pyridine 4-Morpholinoaniline Abiraterone Ethyl Ether 1-nitro-3,5-dimethyl adamantine (NMEM) Vardenafil Bis-sulphonamide(Dimer) 3-(2-aminoethyl) benzene sulfonamide Nabumetone Impurity 5 2,2-dibromo-1-cyclopropyl-2-(2-fluorophenyl)ethan-1-oneRelated products of tetrahydrofuran
You may like
-
Trifluoroacetamidine 95% CAS 354-37-0View Details
354-37-0 -
Trifluoroacetamidine CAS 354-37-0View Details
354-37-0 -
Trifluoroacetamidine CASView Details
-
CAS 354-37-0 TrifluoroacetamidineView Details
354-37-0 -
3-(4-Bromo-3-methyl-2-oxo-2,3-dihydro-1h-benzo[d]imidazol-1-yl)piperidine-2,6-dione 2304754-51-4 99%+View Details
2304754-51-4 -
1126-74-5 99%+View Details
1126-74-5 -
2-Fluoro-6-iodobenzoic acid 99%+View Details
111771-08-5 -
120013-39-0 2,3-Dihydro-5,6-dimethoxy-2-(4-piperidinylmethyl)-1H-inden-1-one hydrochloride 99%+View Details
120013-39-0
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.