Trans-4-(Maleimidomethyl)cyclohexanecarboxylic Acid
- CAS NO.：69907-67-1
- Empirical Formula: C12H15NO4
- Molecular Weight: 237.25
- MDL number: MFCD11519178
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-27 23:13:20
What is Trans-4-(Maleimidomethyl)cyclohexanecarboxylic Acid?
Description
Trans-4-(Maleimidomethyl) cyclohexanecarboxylic Acid is a kind of carboxylate, being well known for its N-hydroxysuccinimide ester derivative (SMCC), which is a useful cross-linking reagent. SMCC is widely used for the generation of stable maleimide-activated carrier proteins, enzyme immunoconjugates and hapten carrier molecule conjugates. It can be used for the coupling of a peptide to an amino group.
References
https://www.aatbio.com/products/smcc-4-n-maleimidomethyl-cyclohexanecarboxylic-acid-n-hydroxysuccinimide-ester-cas-64987-85-5
http://www.sigmaaldrich.com/catalog/product/sigma/m5525?lang=en®ion=US
Zhang, Hongyan, et al. "Antifreeze protein detection using Rhodamine B as photoluminescence label inporous silicon." Current Applied Physics13.4(2013):736-742.
Properties of Trans-4-(Maleimidomethyl)cyclohexanecarboxylic Acid
| Melting point: | 144 °C(Solv: benzene (71-43-2)) |
| Boiling point: | 433.6±18.0 °C(Predicted) |
| Density | 1.329 |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| pka | 4.80±0.10(Predicted) |
| form | powder to crystal |
| color | White to Almost white |
| CAS DataBase Reference | 69907-67-1 |
Safety information for Trans-4-(Maleimidomethyl)cyclohexanecarboxylic Acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for Trans-4-(Maleimidomethyl)cyclohexanecarboxylic Acid
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