Tosufloxacin tosylate
Synonym(s):7-(3-Amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid 4-methylbenzenesulfonate
- CAS NO.：115964-29-9
- Empirical Formula: C26H23F3N4O6S
- Molecular Weight: 576.55
- MDL number: MFCD01711971
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:14:08
What is Tosufloxacin tosylate?
Description
Tosufloxacin tosylate is a new fluoroquinolone antibacterial structurally related to temafloxacin. Mechanistically, it is a microbial DNA topoisomerase inhibitor, useful against beta-lactamase producing organisms. Tosufloxacin tosylate is reported to be particularly effective against Salmonella enteritidis.
Chemical properties
White to Off-White Solid
Originator
Toyama (Japan)
The Uses of Tosufloxacin tosylate
Useful as a therapeutic antimicrobial for the treatment of respiratory infections
The Uses of Tosufloxacin tosylate
Useful as a therapeutic antimicrobial for the treatment of respiratory infections.
What are the applications of Application
Tosufloxacin tosylate is an antibacterial agent that inhibits bacterial DNA gyrase inhibitor
Definition
ChEBI: Tosufloxacin tosylate is a racemate comprising equimolar amounts of (R)- and (S)-tosufloxacin tosylate. It has a role as an antimicrobial agent, an antiinfective agent, a DNA synthesis inhibitor, a hepatotoxic agent and a topoisomerase IV inhibitor. It contains a tosufloxacin(1+), a (S)-tosufloxacin tosylate and a (R)-tosufloxacin tosylate.
brand name
Ozex; Tosuxacin
Properties of Tosufloxacin tosylate
| Melting point: | 251-252°C |
| storage temp. | Refrigerator |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | neat |
| color | White to Pale Yellow |
| BRN | 7617816 |
| CAS DataBase Reference | 115964-29-9 |
Safety information for Tosufloxacin tosylate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Tosufloxacin tosylate
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