tipepidine
- CAS NO.：5169-78-8
- Empirical Formula: C15H17NS2
- Molecular Weight: 275.43
- MDL number: MFCD00552099
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-10-28 16:00:23
What is tipepidine?
Originator
Sotal,G. Ramon
Definition
ChEBI: Tipepidine is a member of piperidines.
Manufacturing Process
From ethyl 1-methylpiperidine-3-carboxylate (which was prepared by hydrogenation of ethyl nicotinate with Ni-catalyst and then by methylation by action dimethyl sulfate) and 2-thienyl magnesium bromide was synthesized 1,1-di(thiophen-2-yl)-2-(3'-N-methylpiperidine), 3-(di-2-thienylmethylene)-1- methylpiperidine was obtained by dehydration of 1,1-di(thiophen-2-yl)-2-(3'- N-methylpiperidine) by action of base.
Therapeutic Function
Antitussive, Expectorant
Properties of tipepidine
| Melting point: | 64-65° |
| Boiling point: | bp4-5 178-184° |
| Density | 1.1947 (rough estimate) |
| refractive index | 1.5300 (estimate) |
| pka | 8.23±0.20(Predicted) |
| form | Solid |
| color | White to light yellow |
Safety information for tipepidine
Computed Descriptors for tipepidine
New Products
Indole Methyl Resin tert-butyl 9-methoxy-3-azaspiro[5.5]undecane-3-carboxylate Boc-His(Boc)-OH 2-CTC Resin 4-Chloro-7-tosy1-7Hpyrrolo[2,3-d]pyrimidine 5,7-Dibromo-1H-indole 2,5-dichloro-N-hydroxy-4,6-dimethylpyridine-3-carboximidamide 2,2-Dimethoxy-7-azaspiro[3.5]nonane hydrochloride 4-chloromethyl-5-methyl-1,3-dioxol-2-one (DMDO-Cl) R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDIIMIDAZOLE 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) N-METHYL INDAZOLE-3-CARBOXYLIC ACID 4-((2-hydroxyethyl)thio)benzoic acid 1-(TERT-BUTOXYCARBONYL)-2-PYRROLIDINONE Methyl 6-methylnicotinate 3-Pyridineacrylic acid tert-Butyl carbazate TETRAHYDRO-2H-PYRAN-3-OL 2-((4-morpholinophenylamino) (methylthio) methylene) malononitrile 3-(4-morpholinophenylamino)-5-amino-1H-pyrazole-4-carbonitrile 2,4-dihydroxybenzaldehyde 1,3-Diethyl-1,3-Diphenylurea Methyl 2-methylquinoline-6-carboxylateRelated products of tetrahydrofuran
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