Tifenamil
- CAS NO.：82-99-5
- Empirical Formula: C20H25NOS
- Molecular Weight: 327.49
- MDL number: MFCD00396147
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 17:34:42
What is Tifenamil?
Originator
Trocinate,Poythress,US,1950
Definition
ChEBI: Tifenamil is a diarylmethane.
Manufacturing Process
The following procedure is described in US Patent 2,510,773: To an ice-cold solution of 13.3 grams of 2-diethylaminoethanethiol in 100 cc of dry benzene is slowly added a solution of 23.05 grams of diphenylacetyl chloride in 200 cc of dry benzene. The mixture is stirred 2 hours, then heated to dissolve the fine white solid that is formed. Upon cooling 31.3 grams of 2- diethylaminoethyl diphenylthiolacetate hydrochloride precipitates. It recrystallizes from a mixture of benzene and petroleum ether (BP 60° to 70°C) as rosettes of tiny needles and melts at 129° to 130°C. From a mixture of absolute ethanol and ethyl acetate it recrystallizes as large, almost transparent prisms.
brand name
Tifenamil is INN.
Therapeutic Function
Spasmolytic
Properties of Tifenamil
| Melting point: | 35-36 °C |
| Boiling point: | 199-200 °C |
| Density | 1.079±0.06 g/cm3(Predicted) |
| pka | 9.42±0.25(Predicted) |
Safety information for Tifenamil
Computed Descriptors for Tifenamil
New Products
2-(2-Chlorophenyl)glycine Propiolic Acid 1-(3-Hydroxy-4-methoxyphenyl)-2-nitroethene (±)-amino(2-fluorophenyl)acetic acid trans-3-Benzyloxy-4-methoxy-beta-nitrostyrene 1-Pentadecanol 2,4-Dihydroxybenzaldehyde Dipropyl disulfide Pyrrolo[1,2-a]pyrimidine-6-carboxylic acid, 4,6,7,8-tetrahydro-4-oxo-, sodium salt (1:1), (6S) Obidoxime hydrochloride API 4 pentyn 1 ol N-Vinylformamide Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 2-Butyn-1-oL N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine Pirtobrutinib intd. 2-Pentyn-1-oL 4-NitrobenzotrifluorideRelated products of tetrahydrofuran
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