tert-Butyl N-(benzyloxy)carbamate
- CAS NO.：79722-21-7
- Empirical Formula: C12H17NO3
- Molecular Weight: 223.27
- MDL number: MFCD00191873
- EINECS: 628-800-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:48:19
What is tert-Butyl N-(benzyloxy)carbamate?
Chemical properties
White powder
The Uses of tert-Butyl N-(benzyloxy)carbamate
tert-Butyl N-(Benzyloxy)carbamate has been used in the synthesis of Deferoxamine Mesylate (D228980), an iron chelating agent used in therapy for patients with sickle cell diseases and iron overload. Studies suggest that it can exert potential antioxidant neuroprotective effects in stroke patients
The Uses of tert-Butyl N-(benzyloxy)carbamate
tert-Butyl N-(benzyloxy)carbamate was used in the preparation of seven-membered cyclic hydroxamic acids. It may be used in the synthesis of 2-(N-formyl-N-hydroxyamino) ethylphosphonate (IPP).
General Description
tert-Butyl N-(benzyloxy)carbamate (tert-butyl benzyloxycarbamate), a protected hydroxylamine, is an N-alkyl-N-benzyloxy carbamate. Its C-N cross coupling reaction with fluorescein ditriflate has been reported. It participates in facile intramolecular cyclization with various carbon nucleophiles to afford functionalized 5- and 6-membered protected cyclic hydroxamic acids.
Properties of tert-Butyl N-(benzyloxy)carbamate
| Melting point: | 45-47 °C (lit.) |
| Density | 1.078±0.06 g/cm3 (20 ºC 760 Torr) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
| form | Solid |
| color | White |
| CAS DataBase Reference | 79722-21-7 |
Safety information for tert-Butyl N-(benzyloxy)carbamate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for tert-Butyl N-(benzyloxy)carbamate
| InChIKey | MZNBNPWFHGWAGH-UHFFFAOYSA-N |
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