Tebufenpyrad

Synonym(s):4-Chloro-N-(4-tert-butylbenzyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide

CAS NO.：119168-77-3
Empirical Formula: C18H24ClN3O
Molecular Weight: 333.86
MDL number: MFCD01632408
EINECS: 242-070-7
SAFETY DATA SHEET (SDS)
Update Date: 2026-04-10 10:27:19

What is Tebufenpyrad?

Chemical properties

Tan Solid

The Uses of Tebufenpyrad

Acaricide.

The Uses of Tebufenpyrad

Tebufenpyrad is a pyrazole acaricide and insecticide commonly used in commercial greenhouses.

Definition

ChEBI: Tebufenpyrad is a pyrazole acaricide and a pyrazole insecticide. It has a role as a mitochondrial NADH:ubiquinone reductase inhibitor.

Metabolic pathway

By incubation of tebufenpyrad with rat liver homogenate, tebufenpyrad undergoes biotransformation to yield the major metabolites N-(4- tert-butylbenzyl)-4-chloro-3-(1-hydroxyethyl)-1- methylpyrazole-5-carboxamide via hydroxylation of the w-1-carbon of the ethyl group and N-[4-(1-carboxy-1- methylethyl)benzyl]-4-chloro-3-ethyl-1-methylpyrazole- 5-carboxamide via oxidation of the methyl group in the tert-butyl moiety to the carboxylic acid derivatives.
When the rat is orally dosed tebufenpyrad, the major metabolism pathway is via both hydroxylation and oxidation reactions to yield N-[4-(1-carboxy-1- methylethyl)benzyl]-4-chloro-3-(1-hydroxyethyl)-1- methylpyrazole-5-carboxamide which is mainly excreted in the urine.

Properties of Tebufenpyrad

Melting point:	61-62°
Boiling point:	468.4±45.0 °C(Predicted)
Density	1.1639 (rough estimate)
refractive index	1.5790 (estimate)
storage temp.	0-6°C
solubility	Benzene (Slightly), DMSO (Slightly), Methanol (Slightly)
pka	13.19±0.46(Predicted)
form	neat
BRN	8636471
CAS DataBase Reference	119168-77-3(CAS DataBase Reference)
EPA Substance Registry System	Tebufenpyrad (119168-77-3)

Safety information for Tebufenpyrad

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08 Environment GHS09
GHS Hazard Statements	H301:Acute toxicity,oral H317:Sensitisation, Skin H332:Acute toxicity,inhalation H373:Specific target organ toxicity, repeated exposure H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P314:Get medical advice/attention if you feel unwell. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P302+P352:IF ON SKIN: wash with plenty of soap and water.