TCS 46B
- CAS NO.：302799-86-6
- Empirical Formula: C22H23N3O
- Molecular Weight: 345.44
- MDL number: MFCD09971137
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-27 17:24:04
What is TCS 46B?
The Uses of TCS 46B
TCS 46b is a subtype-selective NR1A/NR2B NMDA receptor antagonist.
What are the applications of Application
TCS 46b is a subtype-selective NR1A/NR2B NMDA receptor antagonist
Biological Activity
Orally active, subtype-selective NR1A/NR2B NMDA receptor antagonist (IC 50 values are 5.3, 35000 and > 100000 nM for NR1A/2B, NR1A/2A and NR1A/2C receptor subtypes respectively). Potentiates the effect of L-DOPA in 6-OHDA-lesioned rats following oral administration.
Properties of TCS 46B
| Boiling point: | 440.4±38.0 °C(Predicted) |
| Density | 1.24±0.1 g/cm3(Predicted) |
| storage temp. | Store at RT |
| solubility | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| form | Powder |
| pka | 11.51±0.30(Predicted) |
| color | Off-white to light yellow |
Safety information for TCS 46B
Computed Descriptors for TCS 46B
New Products
3-AMINO-3-(2-FLUORO-PHENYL)-PROPIONIC ACID Pentadecanoic acid Hendecanoic acid 2-AMINO-3-METHYLQUINOLINE HYDROCHLORIDE 3-Hydroxypropionitrile DL-3-Amino-3-(2-methoxyphenyl)propionic acid 2-Bromo-5-Iodopyridine 2,3-Diamino-5-Chloropyridine 2-Amino-3-Hydroxypyridine 2,6-Diamino Pyridine 4-Amino-2-Chloropyridine 2-Hydroxy-4-Picoline 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 2-Hydroxy-5-methoxybenzoic acid 2-Cyanopyrimidine Xanthene-9-carboxylic acid 4,4-Diethoxybutanenitrile Methyl 4-amino-2,3-difluoro-5-nitrobenzoate 5-fluoro-1,3-benzodioxole 5-Phenyl-[1,3,4]-thiadiazol-2-amine 2-Chloro-6-nitro benzothiazole 4-Chloro-2-methyl quinoline 2-Amino-4-phenyl-thiazole 2-(Chloromethyl) quinazolin-4(3H)-oneRelated products of tetrahydrofuran
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