SR-95531
Synonym(s):2-(3-Carboxypropyl)-3-amino-6-(4 methoxyphenyl)pyridazinium bromide;GABA A Receptor Antagonist, SR-95531, Gabazine, SR95531, SR 95531;GABAA Receptor Antagonist, SR-95531, Gabazine, SR95531, SR 95531;Gabazine;SR95531 (Gabazine) - CAS 104104-50-9 - Calbiochem
- CAS NO.：104104-50-9
- Empirical Formula: C15H18BrN3O3
- Molecular Weight: 368.23
- MDL number: MFCD09055424
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-11 16:31:51
What is SR-95531?
Description
SR 95531 is a derivative of γ-
The Uses of SR-95531
Gabazine Hydrobromide is a specific GABA receptor antagonist. Does not affect GABA-transaminase or glutamate-decarboxylase activitites.
What are the applications of Application
SR 95531 Hydrobromide is a selective GABAA receptor antagonist
Biological Activity
Selective, competitive GABA A receptor antagonist. Displaces [ 3 H]-GABA from rat brain membranes with a K i of 150 nM. Unlike bicuculline, selectively antagonizes GABA-induced Cl - currents with little action on pentobarbitone-induced currents. Also acts as a low affinity glycine receptor antagonist.
Biochem/physiol Actions
SR-95531 is a specific GABAA receptor antagonist that does not affect GABA-transaminase or glutamate-decarboxylase activities.
Storage
Room temperature
Properties of SR-95531
| Melting point: | 200 °C(Solv: ethanol (64-17-5)) |
| storage temp. | Store at RT |
| solubility | DMSO: 30 mg/mL |
| form | solid |
| color | white |
Safety information for SR-95531
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for SR-95531
New Products
3-AMINO-3-(2-FLUORO-PHENYL)-PROPIONIC ACID Pentadecanoic acid Hendecanoic acid 2-AMINO-3-METHYLQUINOLINE HYDROCHLORIDE 3-Hydroxypropionitrile DL-3-Amino-3-(2-methoxyphenyl)propionic acid 5-Bromo-2-Fluoropyridine 2,3-Diamino-5-Chloropyridine 2-Amino-3-Hydroxypyridine 2,6-Diamino Pyridine 4-Amino-2-Chloropyridine 2-Hydroxy-4-Picoline 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 4-Bromo-3-(ethoxymethyl)benzoic acid 2,4-Dichloro-5-methoxyaniline 4,6-Dichloro-2-(propylthio)pyrimidin-5-amine N2-Isobutyryl-2'-O-methylguanosine 2-chloro-5-methylpyridin-4-amine 4-Bromobenzaldehyde 2-Chloro-6-nitro benzothiazole 2-Amino-4-phenyl-thiazole 4-Chloro-2-methyl quinoline 2-(Chloromethyl) quinazolin-4(3H)-one 5-Phenyl-[1,3,4]-thiadiazol-2-amineRelated products of tetrahydrofuran
![SR95531, [BUTYRYL-2,3-3H]-](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB9684539.gif)
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