SPQ

CAS NO.：83907-40-8
Empirical Formula: C13H15NO4S
Molecular Weight: 281.33
MDL number: MFCD00037592
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 05:21:04

What is SPQ?

Description

SPQ is a fluorescent chloride indicator. Its fluorescence is rapidly quenched by chloride in vitro. It has been used to assess voltage-sensitive chloride transport in placental microvillus vesicles. It has also been used to continuously quantify intracellular calcium efflux induced by parathyroid hormone, forskolin , and phorbol 12-myristate 13-acetate (PMA; ) in isolated human erythrocytes. In addition, SPQ has been used to determine the type of ion conductance induced by the cystic fibrosis transmembrane conductance regulator (CFTR) in HEK293 cells expressing pTrial10-CRTR2. SPQ displays excitation maxima of 320 and 350 nm and an emission maximum of 445 nm.

Chemical properties

Off-White to Tan Cyrstalline Solid

The Uses of SPQ

SPQ offers a simple and yet powerful method to examine and measure membrane chloride transport mechanisms.

What are the applications of Application

6-Methoxy-N-(3-sulfopropyl)quinolinium is a method to examine and measure membrane chloride transport mechanisms

Properties of SPQ

Melting point:	299°C dec.
storage temp.	Inert atmosphere,2-8°C
solubility	Soluble in water, dimethyl sulfoxide
form	powder
color	White
λmax	344 nm
Biological Applications	Chloride indicator; nitrite indicator; diagnosis of diseases caused by elemental imbalances; detecting cancer cells,spores,stress biomarkers; identifying genes; studying chloride–bicarbonate exchange

Safety information for SPQ

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P330:Rinse mouth. P362:Take off contaminated clothing and wash before reuse. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. P405:Store locked up. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P501:Dispose of contents/container to..…